Evidence map›Paper›PMID 35012764›Full record

ArticleJournal of the National Medical Association2022

Effects of race on the outcome of COVID-19 in hospitalized patients.

Getahun Abate, Aniruddh Kapoor, Edward Charbek, Bryan Beck, Qian Wang, Grace C Wang, Mackenzie Steck, Jason Zoglman, Robin R Chambeg, Sharon Frey and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the National Medical Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Getahun AbateDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA. Electronic address: getahun.abate@health.slu.edu.
Aniruddh KapoorDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Edward CharbekDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Bryan BeckDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Qian WangDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Grace C WangDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Mackenzie SteckDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Jason ZoglmanDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Robin R ChambegDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA; SSM St. Louis Network Microbiology, USA.
Sharon FreyDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Daniel F HoftDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Timothy L WiemkenDepartment of Internal Medicine, Saint Louis University, 1100 South Grand Blvd, Doisy Research Center, 8th floor, Saint Louis, MO 63104 USA.
Saint Louis University · US

Funding

Vaccine and Treatment Evaluation Unit at Saint Louis University - DMID 20-0034UM1AI148685 · NIAID · SAINT LOUIS UNIVERSITY · PI Daniel F. Hoft · 2020 to 2026
$34.6M
NIAID NIH HHS UM1 AI148685
6 · The paper itself

Abstract

BACKGROUND AND

aimsRecent reports indicate that African Americans have higher mortality rates from SARS-CoV-2 coronavirus disease 19 (COVID-19) compared to Caucasians, with more marked differences in the Midwest region of the US. This study was performed to study differences in COVID-19 related mortality and hospital length of stay (LOS) between African Americans and Caucasians in Midwest setting, and identify factors associated with mortality and LOS.

methodsData were collected from the electronic health records (EHR) of patients admitted to hospitals in Midwest region of the US. EHR of 471 COVID-19 patients were reviewed.

resultsApproximately 63% were African Americans and 34% Caucasians. One hundred sixteen variables were tested. There was no significant difference in hospital mortality between African Americans and Caucasians (OR 1, 95% CI 0.48-1.94). Older age, Chronic kidney disease, mental status change, mechanical ventilation, vasopressor support, high neutrophil count, elevated AST and ALT, high lung involvement severity score and elevated CRP were associated with mortality in a univariate analysis (P < 0.05). Multivariable modeling indicated that mechanical ventilation was the only factor that predicted mortality (OR 6, 95% CI: 2.94-12.48). The LOS did not differ in African Americans and Caucasians. The use of oxygen via high flow nasal cannula (Survival Estimate 1.6, 95% CI: 1.20-2.26), low estimated glomerular filtration rate (Survival Estimate 1.4, 95% CI: 1.05-1.82) and mechanical ventilation (Survival Estimate 3.5, 95% CI: 2.72-4.37) were predictors of LOS.

conclusionThis study performed in Midwest setting in the US showed that race did not affect in-hospital mortality and LOS. Our analysis demonstrated new predictors of LOS.

Indexed as

COVID-19Black or African AmericanHospitalizationHumansLength of StayRetrospective StudiesSARS-CoV-2White PeopleCOVID-19MortalityOutcomes, Length of hospital stay

Identifiers

PMID35012764
PMCPMC8739651
OpenAlexW4206243835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.