ArticleBiological research2022
Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.
Article in Biological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 52 citations in OpenAlex.
- Genome-wide-association-analysis-based identification of genetic loci and candidate genes associated with seedling emergence rate in super-sweet corn (Zea mays L.).BMC plant biology · 2026Article
- Cadmium toxicity in plants: from transport to tolerance mechanisms.Plant signaling & behavior · 2025Review
- Genome-wide characterization of NRAMP metal transporters reveals functional diversity for heavy metal tolerance in Onobrychis viciifolia.BMC genomics · 2025Article
- Comparative transcriptome analysis reveals the complex response mechanisms of soybean leaves and roots to salt stress.BMC plant biology · 2025Article
- Arbuscular Mycorrhizal Fungi and Their Relationships with the Soil Nutrients and Heavy Metals in Ancient Trees in Blue-Crowned Laughingthrush Habitats.Journal of fungi (Basel, Switzerland) · 2025Article
- Single-cell transcriptomic analyses reveal cellular and molecular patterns of rose petal responses to gray mold infection.Horticulture research · 2025Article
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- Multi-omic analysis identifies the molecular mechanism of hepatocellular carcinoma with cirrhosis.Scientific reports · 2024Article
- CDPK protein in cotton: genomic-wide identification, expression analysis, and conferring resistance to heat stress.BMC plant biology · 2024Article
- The Contribution ofFoods (Basel, Switzerland) · 2024Article
- Heat-stress-induced ROS in maize silks cause late pollen tube growth arrest and sterility.iScience · 2024Article
- Characterization of metallothionein genes from Broussonetia papyrifera: metal binding and heavy metal tolerance mechanisms.BMC genomics · 2024Article
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- Genome-wide identification of heavy-metal ATPases genes in Areca catechu: investigating their functionality under heavy metal exposure.BMC plant biology · 2024Article
- Synergistic interactions of assorted ameliorating agents to enhance the potential of heavy metal phytoremediation.Stress biology · 2024Review
- Metallothionein family genes in kiwifruit: characterization and determining their roles in plant's response to different stresses.Frontiers in plant science · 2024Article
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- The Glutathione System: A Journey from Cyanobacteria to Higher Eukaryotes.Antioxidants (Basel, Switzerland) · 2023Review
- The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity.Plants (Basel, Switzerland) · 2023Review
- Changes in physio-biochemical parameters and expression of metallothioneins in Avena sativa L. in response to drought.Scientific reports · 2023Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaize (Zea mays L.) is a widely cultivated cereal and has been used as an optimum heavy metal phytoremediation crop. Metallothionein (MT) proteins are small, cysteine-rich, proteins that play important roles in plant growth and development, and the regulation of stress response to heavy metals. However, the MT genes for maize have not been fully analyzed so far.
methodsThe putative ZmMT genes were identified by HMMER.The heat map of ZmMT genes spatial expression analysis was generated by using R with the log
resultsA total of 9 ZmMT genes were identified in the whole genome of maize. The results showed that eight of the nine ZmMT proteins contained one highly conserved metallothio_2 domain, while ZmMT4 contained a Metallothio_PEC domain. All the ZmMT proteins could be classified into three major groups and located on five chromosomes. The ZmMT promoters contain a large number of hormone regulatory elements and hormone-related transcription factor binding sites. The ZmMT genes exhibited spatiotemporal specific expression patterns in 23 tissues of maize development stages and showed the different expression patterns in response to Cu, Cd, and Pb heavy metal stresses.
conclusionsWe identified the 9 ZmMT genes, and explored their conserved motif, tissue expression patterns, evolutionary relationship. The expression profiles of ZmMT genes under three kinds of heavy metal stresses (Cu, Cd, Pb) were analyzed. In summary, the expression of ZmMTs have poteintial to be regulated by hormones. The specific expression of ZmMTs in different tissues of maize and the response to different heavy metal stresses are revealed that the role of MT in plant growth and development, and stress resistance to heavy metals.
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