Evidence map›Paper›PMID 35012624›Full record

ArticleBMC research notes2022

Carotid artery velocity time integral and corrected flow time measured by a wearable Doppler ultrasound detect stroke volume rise from simulated hemorrhage to transfusion.

Jon-Émile S Kenny, Igor Barjaktarevic, David C Mackenzie, Mai Elfarnawany, Zhen Yang, Andrew M Eibl, Joseph K Eibl, Chul-Ho Kim, Bruce D Johnson

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Evaluation of hemorrhagic shock and fluid resuscitation in pigs using handless Doppler carotid artery ultrasound.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jon-Émile S KennyHealth Sciences North Research Institute, 56 Walford Rd, Sudbury, ON, P3E 2H2, Canada. jon-emile@heart-lung.org.ORCID http://orcid.org/0000-0002-3654-1146
Igor BarjaktarevicDivision of Pulmonary and Critical Care, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
David C MackenzieDepartment of Emergency Medicine, Maine Medical Center, Portland, ME, USA.
Mai ElfarnawanyFlosonics Medical, 325 Front Street, Toronto, ON, M5V 2Y1, Canada.
Zhen YangFlosonics Medical, 325 Front Street, Toronto, ON, M5V 2Y1, Canada.
Andrew M EiblHealth Sciences North Research Institute, 56 Walford Rd, Sudbury, ON, P3E 2H2, Canada.
Joseph K EiblHealth Sciences North Research Institute, 56 Walford Rd, Sudbury, ON, P3E 2H2, Canada.
Chul-Ho KimHuman Integrative and Environmental Physiology Laboratory, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Bruce D JohnsonHuman Integrative and Environmental Physiology Laboratory, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Health Sciences North · CAMayo Clinic · USTufts University · USUniversity of California, Los Angeles · USUniversity of Toronto · CA

Funding

Office of the Under Secretary of Defense for Health Affairs W81XWH1910591
6 · The paper itself

Abstract

objectiveDoppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrhage and resuscitation comprising approximately 50,000 cardiac cycles, we found a strong, linear correlation between changing stroke volume, and measures from the carotid Doppler signal, however, optimal Doppler thresholds for detecting a 10% stroke volume change were not reported. In this Research Note, we present these thresholds, their sensitivities, specificities and areas under their receiver operator curves (AUROC).

resultsAugmentation of carotid artery maximum velocity time integral and corrected flowtime by 18% and 4%, respectively, accurately captured 10% stroke volume rise. The sensitivity and specificity for these thresholds were identical at 89% and 100%. These data are similar to previous investigations in healthy volunteers monitored by the wearable ultrasound.

Indexed as

Carotid ArteriesWearable Electronic DevicesBlood Flow VelocityCarotid Artery, CommonHemorrhageHumansStroke VolumeUltrasonography, DopplerCarotid DopplerCorrected flow timeStroke volumeVelocity time integral

Identifiers

PMID35012624
PMCPMC8750810
OpenAlexW4205935288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.