Evidence map›Paper›PMID 35012560›Full record

ArticleBMC veterinary research2022

Acute-phase protein concentrations in serum of clinically healthy and diseased European bison (Bison bonasus) - preliminary study.

Małgorzata Pomorska-Mól, Kacper Libera, Magdalena Larska, Michał K Krzysiak

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Małgorzata Pomorska-MólDepartment of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Science, Poznań University of Life Sciences, ul. Wołyńska 35, 60-637, Poznań, Poland. mpomorska@up.poznan.pl.
Kacper LiberaDepartment of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Science, Poznań University of Life Sciences, ul. Wołyńska 35, 60-637, Poznań, Poland.
Magdalena LarskaDepartment of Virology, National Veterinary Research Institute, Al. Partyzantów 57, 24-100, Puławy, Poland.
Michał K KrzysiakBiałowieża National Park, Park Pałacowy 11, 17-230, Białowieża, Poland.
University of Life Sciences in Poznań · PLBiałowieża National Park · PLNational Veterinary Research Institute · PL

Funding

Ministerstwo Edukacji i Nauki 506.514.05.00Narodowe Centrum Nauki DEC-2020/37/B/NZ7/00021
6 · The paper itself

Abstract

backgroundThis is the first report describing levels of APPs in European bison. Serum concentration of acute phase proteins (APPs) may be helpful to assess general health status in wildlife and potentially useful in selecting animals for elimination. Since there is a lack of literature data regarding concentration of APPs in European bisons, establishment of the reference values is also needed.

methodsA total of 87 European bison from Polish populations were divided into two groups: (1) healthy: immobilized for transportation, placing a telemetry collar and routine diagnostic purposes; and (2) selectively culled due to the poor health condition. The serum concentration of haptoglobin, serum amyloid A and α1-acid-glycoprotein were determined using commercial quantitative ELISA assays. Since none of the variables met the normality assumptions, non-parametric Mann-Whitney U test was used for all comparisons. Statistical significance was set at p < 0.05. Statistical analyses were performed using Statistica 13.3 (Tibco, USA).

resultsThe concentration of haptoglobin and serum amyloid A was significantly higher in animals culled (euthanised) due to the poor condition in respect to the clinically healthy European bison. The levels of α1-acid-glycoprotein did not show statistical difference between healthy and sick animals.

conclusionsCorrelation between APPs concertation and health status was proven, therefore the determination of selected APPs may be considered in future as auxiliary predictive tool in assessing European bison health condition.

Indexed as

Acute-Phase ProteinsBisonAnimalsHaptoglobinsSerum Amyloid A ProteinAcute-Phase ProteinsHaptoglobinsSerum Amyloid A ProteinAcute phase proteinsAGPEuropean bisonHpSAAWildlife management

Identifiers

PMID35012560
PMCPMC8744219
OpenAlexW4206565737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.