Evidence map›Paper›PMID 35012438›Full record

ArticleBioengineered2022

Long non-coding RNA p53 upregulated regulator of p53 levels (PURPL) promotes the development of gastric cancer.

Zhonghua Cheng, Jing Hong, Nan Tang, Fenghua Liu, Shuo Gu, Zhen Feng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhonghua ChengDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Jing HongDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Nan TangDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Fenghua LiuDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Shuo GuDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Zhen FengDepartment of Gastroenterology, The Central Hospital of Xuhui District, Xuhui Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
The First Affiliated Hospital, Sun Yat-sen University · CNZhongshan Hospital · CNShanghai Xuhui Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC), one of the most prevalent malignancies across the world, has an increasing incidence rate. Long non-coding RNA (lncRNA) PURPL (also referred to as LINC01021) has been demonstrated to influence malignant GC behaviors and partake in other cancers. Notwithstanding, reports pertaining to the underlying mechanism of PURPL in GC haven't been rarely seen. Presently,

Indexed as

Up-RegulationAnimalsApoptosisCell CycleCell Line, TumorCell ProliferationDNA-Binding ProteinsGene Expression Regulation, NeoplasticHumansMaleMiceMicroRNAsNeoplasm TransplantationPhosphatidylinositol 3-KinasesRNA, Long NoncodingSignal TransductionDNA-Binding ProteinsMicroRNAsMIRN137 microRNA, humanPhosphatidylinositol 3-KinasesRNA, Long NoncodingTranscription FactorsTumor Suppressor Protein p53ZBTB7A protein, humanGastric cancermiR-137progressionPURPLsignaling pathwayZBTB7A

Identifiers

PMID35012438
PMCPMC8805877
OpenAlexW4206263076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.