Evidence map›Paper›PMID 35012344›Full record

ArticlemBio2022

Disentangling the Evolutionary History of Feo, the Major Ferrous Iron Transport System in Bacteria.

Camilo Gómez-Garzón, Jeffrey E Barrick, Shelley M Payne

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. The structure of the full catalytic cycle ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Structural Determinants ofbioRxiv : the preprint server for biology · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Camilo Gómez-GarzónDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0003-4971-8999
Jeffrey E BarrickDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0003-0888-7358
Shelley M PayneDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0003-3112-4340
The University of Texas at Austin · US

Funding

Characterization of the ferrous iron transporter Feo in Vibrio choleraeR01AI091957 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI PAYNE, SHELLEY M. · 2011 to 2021
$3.9M
NIAID NIH HHS R01 AI091957
6 · The paper itself

Abstract

Iron acquisition is essential for almost all living organisms. In certain environments, ferrous iron is the most prevalent form of this element. Feo is the most widespread system for ferrous iron uptake in bacteria and is critical for virulence in some species. The canonical architecture of Feo consists of a large transmembrane nucleoside triphosphatase (NTPase) protein, FeoB, and two accessory cytoplasmic proteins, FeoA and FeoC. The role of the latter components and the mechanism by which Feo orchestrates iron transport are unclear. In this study, we conducted a comparative analysis of Feo protein sequences to gain insight into the evolutionary history of this transporter. We identified instances of how horizontal gene transfer contributed to the evolution of Feo. Also, we found that FeoC, while absent in most lineages, is largely present in the

Indexed as

Bacterial ProteinsNucleoside-TriphosphataseBacteriaIronMembrane Transport ProteinsBacterial ProteinsIronMembrane Transport ProteinsNucleoside-Triphosphatasebacteriabacterial evolutionbioinformaticsevolutionFeoiron transportphylogeneticsVibrio cholerae

Identifiers

PMID35012344
PMCPMC8749426
OpenAlexW4206602946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.