ArticlemBio2022
Small-Molecule Mn Antioxidants in Caenorhabditis elegans and Deinococcus radiodurans Supplant MnSOD Enzymes during Aging and Irradiation.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- DrPitA-mediated enrichment of intracellular manganese and phosphate contributes to oxidative stress resistance ofApplied and environmental microbiology · 2026Article
- In Vitro Evaluation of Redox-Associated Responses Induced by Mud Extract in L929 and RAW 264.7 Cells.Antioxidants (Basel, Switzerland) · 2026Article
- Feeding Drosophila highly radioresistant fungi improves survival and gut morphology following acute gamma radiation exposure.Scientific reports · 2025Article
- Article
- The Role of the MntABC Transporter System in the Oxidative Stress Resistance ofInternational journal of molecular sciences · 2025Article
- Article
- Prophylactically Feeding Manganese toAntioxidants (Basel, Switzerland) · 2025Article
- The ternary complex of MnProceedings of the National Academy of Sciences of the United States of America · 2024Article
- DdrC, a unique DNA repair factor from D. radiodurans, senses and stabilizes DNA breaks through a novel lesion-recognition mechanism.Nucleic acids research · 2024Article
- An inorganic mineral-based protocell with prebiotic radiation fitness.Nature communications · 2023Article
- New Insights into Radio-Resistance Mechanism Revealed by (Phospho)Proteome Analysis ofInternational journal of molecular sciences · 2023Article
- Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes inBiology · 2023Article
- Effects of Desiccation and Freezing on Microbial Ionizing Radiation Survivability: Considerations for Mars Sample Return.Astrobiology · 2022Article
- Whole-cell vaccine candidates induce a protective response against virulentFrontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 8 institutions in 4 countries.
Elena K Gaidamakova *Department of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Ajay Sharma *Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
Vera Y Matrosova *Department of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Olga GrichenkoDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Robert P VolpeDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Rok TkavcDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Isabel H ConzeDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Polina KlimenkovaDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Irina BalyginaDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
William H HorneDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Cene GostinčarDepartment of Biology, University of Ljubljana, Biotechnical Faculty, Ljubljana, Slovenia.ORCID 0000-0002-0149-3674
Xiao ChenIGM Biosciences, Mountain View, California, USA.
Kira S MakarovaNational Center for Biotechnology Informationgrid.419234.9, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Igor ShuryakCenter for Radiological Research, Columbia University Irving Medical Center, New York, New York, USA.
Chandra SrinivasanDepartment of Chemistry & Biochemistry, California State University, Dominguez Hillsgrid.253556.2, California, USA.
Belinda Jackson-ThompsonDepartment of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
Brian M Hoffman *Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
Michael J Daly *Department of Pathology, School of Medicine, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.ORCID 0000-0003-1496-5930
Henry M. Jackson Foundation · USUniformed Services University of the Health Sciences · USNorthwestern University · USCalifornia State University, Dominguez Hills · USColumbia University Irving Medical Center · USIGM Biosciences (United States) · USNational Institutes of Health · USUniversity of Ljubljana · SI
Funding
Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7MManganese Metabolism in C. elegansR15GM090169 · NIGMS · CALIFORNIA STATE UNIVERSITY FULLERTON · PI SRINIVASAN, CHANDRA · 2010 to 2010
$219kNIGMS NIH HHS R01 GM111097NIGMS NIH HHS R15 GM090169
Abstract
Denham Harman's oxidative damage theory identifies superoxide (O
Indexed as
AntioxidantsDeinococcusAgingAnimalsCaenorhabditis elegansManganeseReactive Oxygen SpeciesSuperoxide DismutaseSuperoxidesAntioxidantsManganeseReactive Oxygen SpeciesSuperoxide DismutaseSuperoxidesagingCaenorhabditisDeinococcusdesiccationEPRionizing radiationLactobacillusMn antioxidantsMnSODreactive oxygen speciesROSsuperoxide dismutase
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.