ArticlePolymers2022
Polyhydroxyalkanoates-Based Nanoparticles as Essential Oil Carriers.
Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Review
- Next-Generation Bioplastics for Food Packaging: Sustainable Materials and Applications.Materials (Basel, Switzerland) · 2025Review
- Poly(3-hydroxybutyrate)/Clay/Essential Oils Bionanocomposites Incorporating Biochar: Thermo-Mechanical and Antioxidant Properties.Polymers · 2025Article
- Rhamnolipid-Modified PHB-Ectoine Nanoparticles for Multifunctional Skin Protection Against UVB, Irritation, and Bacteria.ACS omega · 2025Article
- Boosting Food Packaging Sustainability Through the Valorization of Agri-Food Waste and By-Products.Polymers · 2025Review
- Effect of surfactants and polymer composition on the characteristics of polyhydroxyalkanoate nanoparticles.ADMET & DMPK · 2025Article
- Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics.Current drug delivery · 2025Review
- Investigation of Guar Gum and Xanthan Gum Influence on Essential Thyme Oil Emulsion Properties and Encapsulation Release Using Modeling Tools.Foods (Basel, Switzerland) · 2024Article
- Spray-dried cyclophosphamide-loaded polyhydroxyalkanoate microparticles: design and characterization.ADMET & DMPK · 2024Article
- Novel Biodegradable Nanoparticulate Chain-End Functionalized Polyhydroxybutyrate-Caffeic Acid with Multifunctionalities for Active Food Coatings.ACS sustainable chemistry & engineering · 2023Article
- Review
- Novel Production Methods of Polyhydroxyalkanoates and Their Innovative Uses in Biomedicine and Industry.Molecules (Basel, Switzerland) · 2022Review
- Alternative Controlling Agent ofNanomaterials (Basel, Switzerland) · 2022Article
- Pulsatile Controlled Release and Stability Evaluation of Polymeric Particles ContainingMaterials (Basel, Switzerland) · 2022Article
- An Up-To-Date Review Regarding Cutaneous Benefits ofAntibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Plant-derived essential oils (EOs) represent a green alternative to conventional antimicrobial agents in food preservation. Due to their volatility and instability, their application is dependent on the development of efficient encapsulation strategies allowing their protection and release control. Encapsulation in Polyhydroxyalkanoate (PHA)-based nanoparticles (NPs) addresses this challenge, providing a biodegradable and biobased material whose delivery properties can be tuned by varying polymer composition. In this work, EO from Mexican oregano was efficiently encapsulated in Polyhydroxybutyrate (PHB) and Poly-3-hydroxybutyrate-co-hydroxyhexanoate (PHB-HHx)-based NPs by solvent evaporation technique achieving high encapsulation efficiency, (>60%) and loading capacity, (about 50%). The obtained NPs displayed a regular distribution with a size range of 150-210 nm. In vitro release studies in food simulant media were fitted with the Korsmeyer-Peppas model, indicating diffusion as the main factor controlling the release. The cumulative release was affected by the polymer composition, possibly related to the more amorphous nature of the copolymer, as confirmed by WAXS and DSC analyses. Both the EO-loaded nanosystems displayed antimicrobial activity against Micrococcus luteus, with PHB-HHx-based NPs being even more effective than the pure EO. The results open the way to the effective exploitation of the developed nanosystems in active packaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.