Evidence map›Paper›PMID 35012000›Full record

ArticleJournal of clinical medicine2022

360° Ab-Interno Schlemm's Canal Viscodilation with OMNI Viscosurgical Systems for Open-Angle Glaucoma-Midterm Results.

Giacomo Toneatto, Marco Zeppieri, Veronica Papa, Laura Rizzi, Carlo Salati, Andrea Gabai, Paolo Brusini

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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  11. It Is All about Pressure.Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giacomo ToneattoDepartment of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0001-8994-1947
Marco ZeppieriDepartment of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0003-0999-5545
Veronica PapaDepartment of Ophthalmology, Policlinico "Città di Udine", 33100 Udine, Italy.
Laura RizziDepartment of Economics and Statistics, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-2470-3953
Carlo SalatiDepartment of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.
Andrea GabaiDepartment of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0002-3865-3336
Paolo BrusiniDepartment of Ophthalmology, Policlinico "Città di Udine", 33100 Udine, Italy.ORCID 0000-0003-0855-5775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effectiveness of ab-interno microcatheterization and 360° viscodilation of Schlemm's canal (SC) performed with OMNI viscosurgical system in open angle glaucoma (OAG) together or not with phacoemulsification.

settingTwo surgical sites.

designRetrospective, observational.

methodsEighty eyes from 73 patients with mild to moderate OAG underwent ab- interno SC viscodilation performed with OMNI system. Fifty eyes (Group 1) underwent only SC viscodilation, while 30 eyes (Group 2) underwent glaucoma surgery + cataract extraction. Primary success endpoint at 12 months was an intraocular pressure (IOP) reduction higher than 25% from baseline with an absolute value of 18 mmHg or lower, either on the same number or fewer ocular hypotensive medications, without further interventions. Secondary effectiveness endpoints included mean IOP, number of medications and comparison of outcomes between groups. Safety endpoints consisted of best-corrected visual acuity (BCVA), adverse events (AEs), and subsequent surgical procedures.

resultsPrimary success was achieved in 40.0% and 67.9% in Groups 1 and 2, respectively. Mean IOP at 12-month follow-up showed a significant reduction in both groups (from 23.0 to 15.6 mmHg,

conclusionsViscodilation of SC using OMNI viscosurgical systems is safe and relatively effective in reducing IOP in adult patients with OAG.

Indexed as

cataract extractionminimally invasive glaucoma surgeries (MIGS)OMNI viscosurgical systemopen angle glaucoma (OAG)Schlemm’s canal viscodilationtrabeculotomy

Identifiers

PMID35012000
PMCPMC8745878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.