Evidence map›Paper›PMID 35011972›Full record

ArticleJournal of clinical medicine2021

Effect of Antipsychotic Treatment on Neutrophil-to-Lymphocyte Ratio during Hospitalization for Acute Psychosis in the Course of Schizophrenia-A Cross-Sectional Retrospective Study.

Bartosz Dawidowski, Grzegorz Grelecki, Adam Biłgorajski, Piotr Podwalski, Błażej Misiak, Jerzy Samochowiec

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bartosz DawidowskiDepartment of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0003-0677-4341
Grzegorz GreleckiDepartment of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.
Adam BiłgorajskiDepartment of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.
Piotr PodwalskiDepartment of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.
Błażej MisiakDepartment of Psychiatry, Division of Consultation Psychiatry and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0002-5392-6398
Jerzy SamochowiecDepartment of Psychiatry, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0003-1438-583X

Funding

Polish Minister of Science and Higher Education 002/RID/2018/2019
6 · The paper itself

Abstract

backgroundStudies have shown that there are deviations in the results of peripheral blood counts, which lead to increased values of the neutrophils-to-lymphocytes ratio (NLR) in schizophrenia. Antipsychotic drugs have proven to lower the levels of pro-inflammatory cytokines and a growing number of studies indicate a similar effect on NLR values.

methodsWe identified inpatients with schizophrenia and collected data of NLR at the beginning (NLR

resultsAfter the inclusion and exclusion process the records of 40 patients (n

conclusionsThe study confirmed the lowering effect of antipsychotics on NLR values in psychosis. The NLR may potentially be a tool for assessing response to treatment with antipsychotics.

Indexed as

antipsychoticshypothyroidisminflammatory markersneutrophil-to-lymphocyte ratioschizophrenia

Identifiers

PMID35011972
PMCPMC8745875

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.