Evidence map›Paper›PMID 35011916›Full record

ArticleJournal of clinical medicine2021

Heart Team for Left Atrial Appendage Occlusion: A Patient-Tailored Approach.

Stefano Branzoli, Fabrizio Guarracini, Massimiliano Marini, Giovanni D'Onghia, Daniele Penzo, Silvio Piffer, Dimitri Peterlana, Angelo Graffigna, Michele Massimo Gulizia, Sandro Gelsomino and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Stefano BranzoliDepartment of Cardiac Surgery, UZ Brussel, Av. du Laerbeek 101, 1090 Brussels, Belgium.
Fabrizio GuarraciniDepartment of Cardiology, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Massimiliano MariniDepartment of Cardiology, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Giovanni D'OnghiaDepartment of Cardiology, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Daniele PenzoDepartment of Anesthesia, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Silvio PifferNeurology Unit, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Dimitri PeterlanaDivision of General Internal Medicine Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Angelo GraffignaCardiac Surgery Unit, Santa Chiara Hospital, Largo Medaglie d'oro, 38122 Trento, Italy.
Michele Massimo GuliziaCardiology Complex Unit, Garibaldi Nesima Hospital, 95122 Catania, Italy.
Sandro GelsominoDepartment of Cardiac Surgery, UZ Brussel, Av. du Laerbeek 101, 1090 Brussels, Belgium.ORCID 0000-0002-7746-989X
Mark La MeirDepartment of Cardiac Surgery, UZ Brussel, Av. du Laerbeek 101, 1090 Brussels, Belgium.
Ospedale Santa Chiara · ITOspedale Garibaldi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeLeft atrial appendage occlusion (LAAO) is an accepted therapeutic option for stroke prevention; however, the ideal technique and device have not yet been identified. In this study we evaluate the potential role of a heart team approach for patients contraindicated for oral anticoagulants and indicated for left atrial appendage closure, to minimize risk and optimize benefit in a patient-centered decision-making process.

methodsForty patients were evaluated by the heart team for appendage occlusion. Variables considered were CHA

resultsMean duration of procedures and hospital stay were comparable. All patients had complete exclusion of the appendage; at a mean follow up of 33.1 ± 14.1 months, no neurological or hemorrhagic events were reported.

conclusionsA heart team approach may improve the decision-making process for stroke and hemorrhage prevention, where LAAO is a therapeutic option. Percutaneous and thoracoscopic appendage occlusion seem to be comparably safe and effective. An epicardial LAAO could be advisable in patients for whom the risk of bleeding is estimated as being too high for post-procedural antiplatelet therapy.

Indexed as

contraindication oral anticoagulantsheart teamleft atrial appendage occlusionpercutaneous procedurethoracoscopic surgery

Identifiers

PMID35011916
PMCPMC8745334
OpenAlexW4200133906

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.