Evidence map›Paper›PMID 35011914›Full record

ArticleJournal of clinical medicine2021

Male vs. Female Differences in Responding to Oxygen-Ozone Autohemotherapy (O

Salvatore Chirumbolo, Luigi Valdenassi, Marianno Franzini, Sergio Pandolfi, Giovanni Ricevuti, Umberto Tirelli

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Article
  3. Article
  4. Ozone therapy in musculoskeletal medicine: a comprehensive review.European journal of medical research · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salvatore ChirumboloDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-1789-8307
Luigi ValdenassiItalian Society of Oxygen Ozone Therapy (SIOOT), University of Pavia, 27100 Pavia, Italy.
Marianno FranziniItalian Society of Oxygen Ozone Therapy (SIOOT), University of Pavia, 27100 Pavia, Italy.
Sergio PandolfiItalian Society of Oxygen Ozone Therapy (SIOOT), University of Pavia, 27100 Pavia, Italy.
Giovanni RicevutiItalian Society of Oxygen Ozone Therapy (SIOOT), University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3422-2747
Umberto TirelliTirelli Medical Group, 33170 Pordenone, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a syndrome that has fatigue as its major symptom. Evidence suggests that ozone is able to relieve ME/CFS-related fatigue in affected patients. (2) Objective: To evaluate whether differences exist between males and females in ozone therapy outputs in ME/CFS. (3) Methods: In total, 200 patients previously diagnosed with ME/CFS (mean age 33 ± 13 SD years) underwent treatment with oxygen-ozone autohemotherapy (O

Indexed as

clinical trialfatigueME/CFSoxygen–ozone therapyozone

Identifiers

PMID35011914
PMCPMC8745436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.