Evidence map›Paper›PMID 35011862›Full record

ArticleJournal of clinical medicine2021

Usefulness of the MAGGIC Score in Predicting the Competing Risk of Non-Sudden Death in Heart Failure Patients Receiving an Implantable Cardioverter-Defibrillator: A Sub-Analysis of the OBSERVO-ICD Registry.

Marco Canepa, Pietro Palmisano, Gabriele Dell'Era, Matteo Ziacchi, Ernesto Ammendola, Michele Accogli, Eraldo Occhetta, Mauro Biffi, Gerardo Nigro, Pietro Ameri and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02735811 (The Italian Multicentric OBSERVational Registry on Long-term Outcome of ICD Patients), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02735811 unknown statusnot on this map

The Italian Multicentric OBSERVational Registry on Long-term Outcome of ICD Patients (OBSERVO-ICD Registry)

TypeobservationalSponsorAzienda Ospedaliera Cardinale G. PanicoRan2015 to 2016Enrolled1,300ConditionsCardiomyopathiesArmsAssesment of long-term outcome of ICD patients
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marco CanepaCardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiovascular Network, 16100 Genova, Italy.
Pietro PalmisanoDivision of Cardiology, Cardinale G. Panico Hospital, 73039 Tricase, Italy.ORCID 0000-0001-6705-6218
Gabriele Dell'EraDivision of Cardiology, Hospital Maggiore Della Carità, 28100 Novara, Italy.
Matteo ZiacchiInstitute of Cardiology, University Hospital Policlinic S. Orsola-Malpighi, 40121 Bologna, Italy.ORCID 0000-0003-3617-2739
Ernesto AmmendolaDivision of Cardiology, Vincenzo Monaldi Hospital, 80100 Naples, Italy.
Michele AccogliDivision of Cardiology, Cardinale G. Panico Hospital, 73039 Tricase, Italy.
Eraldo OcchettaDivision of Cardiology, Hospital Maggiore Della Carità, 28100 Novara, Italy.
Mauro BiffiInstitute of Cardiology, University Hospital Policlinic S. Orsola-Malpighi, 40121 Bologna, Italy.
Gerardo NigroDivision of Cardiology, Vincenzo Monaldi Hospital, 80100 Naples, Italy.ORCID 0000-0003-1776-8449
Pietro AmeriCardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiovascular Network, 16100 Genova, Italy.
Giulia StronatiCardiology and Arrhythmology Clinic, Marche Polytechnic University, 60121 Ancona, Italy.
Italo PortoCardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, IRCCS Italian Cardiovascular Network, 16100 Genova, Italy.
Antonio Dello RussoCardiology and Arrhythmology Clinic, Marche Polytechnic University, 60121 Ancona, Italy.
Federico GuerraCardiology and Arrhythmology Clinic, Marche Polytechnic University, 60121 Ancona, Italy.ORCID 0000-0001-5394-1312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of prognostic risk scores in predicting the competing risk of non-sudden death in heart failure patients with reduced ejection fraction (HFrEF) receiving an implantable cardioverter-defibrillator (ICD) is unclear. To this goal, we evaluated the accuracy and usefulness of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) score. The present analysis included 1089 HFrEF ICD recipients enrolled in the OBSERVO-ICD registry (NCT02735811). During a median follow-up of 36 months (1st-3rd IQR 25-48 months), 193 patients (17.7%) experienced at least one appropriate ICD therapy, and 133 patients died (12.2%) without experiencing any ICD therapy. The frequency of patients receiving ICD therapies was stable around 17-19% across increasing tertiles of 3-year MAGGIC probability of death, whereas non-sudden mortality increased (6.4% to 9.8% to 20.8%,

Indexed as

competing riskICD therapiesimplantable cardioverter-defibrillatorsudden cardiac death

Identifiers

PMID35011862
PMCPMC8745772

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.