ArticleJournal of clinical medicine2021
Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) for Lymphedema Prevention after Axillary Lymph Node Dissection-A Single Institution Experience and Feasibility of Technique.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preventing Secondary Lymphedema: A Systematic Review and Meta-Analysis on the Efficacy of Immediate Lymphovenous Anastomosis.Journal of surgical oncology · 2025Pooled it
- Simplified LYMPHA for Prevention of Breast Cancer-Related Lymphedema After Axillary Dissection: Initial Feasibility Experience from South Asia.European journal of breast health · 2026Article
- LYMPHA Technique to Prevent Arm Lymphedema After Breast Cancer Treatment: A Single-Center Study Based on a 15-Year Follow-Up Period.Annals of surgical oncology · 2026Article
- Breast cancer-related lymphedema of the upper limb: integrating early surveillance and functional surgery into a synergistic management paradigm.Frontiers in surgery · 2026Review
- Clinical Pharmacokinetic-Pharmacodynamic Relationships of Pharmacological Strategies for Attenuating p-Cresyl Sulfate in Patients with Kidney Disease.Clinical pharmacokinetics · 2025Article
- BJS commission on the surgical management of the axilla in breast cancer.The British journal of surgery · 2025Article
- Long-Term Outcomes of Lymphedema After Immediate Lymphatic Reconstruction Following Axillary Lymph Node Dissection.Annals of surgical oncology · 2025Article
- A Single Institution Experience With Immediate Lymphatic Reconstruction: Impact of Insurance Coverage on Risk Reduction.Journal of surgical oncology · 2025Article
- Article
- The Approach to Multidisciplinary Oncologic Breast Care.Seminars in plastic surgery · 2025Review
- Preventing Breast Cancer-Related Lymphedema: A Comprehensive Analysis of a 9-Year Single-Center Experience of Prophylactic Lymphovenous Bypass.Annals of surgical oncology · 2025Article
- Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review.Medical oncology (Northwood, London, England) · 2024Review
- Supermicrosurgical lymphovenous anastomosis.Journal of the Chinese Medical Association : JCMA · 2024Review
- Trends in Immediate Lymphatic Reconstruction.Cureus · 2024Article
- Prevention of Breast Cancer-Related Lymphedema: An Up-to-Date Systematic Review of Different Surgical Approaches.Journal of clinical medicine · 2024Review
- Prophylactic Lymphovenous Bypass at the Time of Axillary Lymph Node Dissection Decreases Rates of Lymphedema.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Article
- St. Gallen/Vienna 2023: Optimization of Treatment for Patients with Primary Breast Cancer - A Brief Summary of the Consensus Discussion.Breast care (Basel, Switzerland) · 2023Review
- Capturing the patient experience in systemic lupus erythematosus: Are widely used measures fit-for-purpose and adherent to FDA PRO guidance recommendations?Journal of patient-reported outcomes · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While surgical options exist to treat lymphedema after axillary lymph node dissection (ALND), the lymphatic microsurgical preventive healing approach (LYMPHA) has been introduced as a preventive measure performed during the primary surgery, thus avoiding the morbidity associated with lymphedema. Here, we highlight details of our operative technique and review postoperative outcomes. For our patients, limb measurements and body composition analyses were performed pre- and postoperatively. Intraoperatively, axillary reverse lymphatic mapping was performed with indocyanine green (ICG) and lymphazurin. SPY-PHI imaging was used to visualize the ICG uptake into axillary lymphatics. Cut lymphatics from excised nodes were preserved for lymphaticovenous anastomosis (LVA). At the completion of the microanastomosis, ICG was visualized draining from the lymphatic through the recipient vein. A retrospective review identified nineteen patients who underwent complete or partial mastectomy with ALND and subsequent LYMPHA over 19 months. The number of LVAs performed per patient ranged between 1-4 per axilla. The operating time ranged from 32-95 min. There were no surgical complications, and thus far one patient developed mild lymphedema with an average follow up of 10 months. At the clinic follow up, ICG and SPY angiography were used to confirm intact lymphatic conduits with an uptake of ICG across the axilla. This study supports LYMPHA as a feasible and effective method for lymphedema prevention.
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