Evidence map›Paper›PMID 35011818›Full record

ArticleJournal of clinical medicine2021

Association between Non-HDL-C/HDL-C Ratio and Carotid Intima-Media Thickness in Post-Menopausal Women.

Arcangelo Iannuzzi, Francesco Giallauria, Marco Gentile, Paolo Rubba, Giuseppe Covetti, Alessandro Bresciani, Emilio Aliberti, Gilanluigi Cuomo, Camilla Panico, Maria Tripaldella and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
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  7. Association Between Carotid Intima-Media Thickness and Novel Lipid Parameters in Hypertensive Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Arcangelo IannuzziDepartment of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.ORCID 0000-0001-6586-8597
Francesco GiallauriaDepartment of Translational Medical Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0003-4119-9397
Marco GentileDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.ORCID 0000-0003-3744-6375
Paolo RubbaDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.
Giuseppe CovettiDepartment of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.
Alessandro BrescianiDepartment of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.
Emilio AlibertiDepartment of Gastroenterology, North Tees University Hospital, Stockton-on-Tees TS19 8PE, UK.
Gilanluigi CuomoDepartment of Translational Medical Sciences, Federico II University of Naples, 80131 Naples, Italy.
Camilla PanicoDiagnostic and Interventional Radiology-Policlinico Gemelli Foundation, 00168 Rome, Italy.
Maria TripaldellaDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.
Maria Ausilia GiustiDiabetes and Islet Transplantation Unit, Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT (Istituto Mediterraneo per I Trapianti e Terapie ad alta specializzazione), UPMC Italy, 90127 Palermo, Italy.
Alessandro MattinaDiabetes and Islet Transplantation Unit, Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT (Istituto Mediterraneo per I Trapianti e Terapie ad alta specializzazione), UPMC Italy, 90127 Palermo, Italy.ORCID 0000-0003-3458-0894
Gabriella IannuzzoDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.ORCID 0000-0002-7392-5544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherogenic lipoproteins (particularly, very low-density lipoproteins, VLDL) are associated with subclinical atherosclerosis. The present study aims at evaluating whether routinely analysed lipid parameters are associated with carotid intima-media thickness, a proxy for subclinical atherosclerosis. Lipid parameters from 220 post-menopausal women undergoing ultrasound investigation of the carotid arteries were analysed. Forty-five percent of women showed subclinical atherosclerosis on carotid ultrasound. The mean carotid intima-media thickness was 1.26 ± 0.38 mm. The mean value of the non-HDL-C/HDL-C ratio was 3.1 ± 1.2. Univariate analysis showed a significant association between non-HDL-C/HDL-C ratio and intima-media thickness (r = 0.21,

Indexed as

carotid intima-media thichnessnon-HDL-C/HDL-C ratiopost-menopausal women

Identifiers

PMID35011818
PMCPMC8745439

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.