Evidence map›Paper›PMID 35011810›Full record

ArticleJournal of clinical medicine2021

COVID-19 Patient Management in Outpatient Setting: A Population-Based Study from Southern Italy.

Salvatore Crisafulli, Valentina Ientile, Luca L'Abbate, Andrea Fontana, Claudio Linguiti, Sonia Manna, Mariangela Mercaldo, Claudia Pagliaro, Michele Vezzaro, Katia Santacà and 9 more

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In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Salvatore CrisafulliDepartment of Medicine, University of Verona, 37134 Verona, Italy.
Valentina IentileDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.
Luca L'AbbateDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Andrea FontanaUnit of Biostatistics, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0002-6660-5315
Claudio LinguitiCaserta Local Health Unit, 81100 Caserta, Italy.
Sonia MannaCaserta Local Health Unit, 81100 Caserta, Italy.
Mariangela MercaldoCaserta Local Health Unit, 81100 Caserta, Italy.
Claudia PagliaroCaserta Local Health Unit, 81100 Caserta, Italy.
Michele VezzaroDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Katia SantacàDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Riccardo LoraDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Ugo MorettiDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Chiara RenoDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-7933-2141
Maria Pia FantiniDepartment of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-3257-6552
Salvatore CorraoDepartment of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-5621-1374
Donato BarbatoIQVIA, 20124 Milan, Italy.
Michele TariCaserta Local Health Unit, 81100 Caserta, Italy.
Gianluca TrifiròDepartment of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-1147-7296
The Ita-Covid Cov-Out Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on treatments for early-stage COVID-19 in outpatient setting is sparse. We explored the pattern of use of drugs prescribed for COVID-19 outpatients' management in Southern Italy in the period February 2020-January 2021. This population-based cohort study was conducted using COVID-19 surveillance registry from Caserta Local Health Unit, which was linked to claims databases from the same catchment area. The date of SARS-CoV-2 infection diagnosis was the index date (ID). We evaluated demographic and clinical characteristics of the study drug users and the pattern of use of drugs prescribed for outpatient COVID-19 management. Overall, 40,030 patients were included in the analyses, with a median (IQR) age of 44 (27-58) years. More than half of the included patients were asymptomatic at the ID. Overall, during the study period, 720 (1.8%) patients died due to COVID-19. Azithromycin and glucocorticoids were the most frequently prescribed drugs, while oxygen was the less frequently prescribed therapy. The cumulative rate of recovery from COVID-19 was 84.2% at 30 days from ID and it was lower among older patients. In this study we documented that the drug prescribing patterns for COVID-19 treatment in an outpatient setting from Southern Italy was not supported from current evidence on beneficial therapies for early treatment of COVID-19, thus highlighting the need to implement strategies for improving appropriate drug prescribing in general practice.

Indexed as

COVID-19Italyoutpatients

Identifiers

PMID35011810
PMCPMC8745524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.