Evidence map›Paper›PMID 35011808›Full record

ArticleJournal of clinical medicine2021

Comparison of Acquired Activated Protein C Resistance, Using the CAT and ST-Genesia

Maria Efthymiou, Philip J Lane, David Isenberg, Hannah Cohen, Ian J Mackie

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria EfthymiouHaemostasis Research Unit, Department of Haematology, University College London, London WC1E 6HX, UK.
Philip J LaneHaemostasis Research Unit, Department of Haematology, University College London, London WC1E 6HX, UK.ORCID 0000-0001-9335-1819
David IsenbergDepartment of Rheumatology, University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.
Hannah CohenHaemostasis Research Unit, Department of Haematology, University College London, London WC1E 6HX, UK.
Ian J MackieHaemostasis Research Unit, Department of Haematology, University College London, London WC1E 6HX, UK.ORCID 0000-0002-7393-2365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcquired activated protein C resistance (APCr) has been identified in antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

objectiveTo assess agreement between the ST-Genesia

methodsAPCr was assessed with the ST-Genesia using STG-ThromboScreen and with the CAT using recombinant human activated protein C and Protac

resultsAPCr values were consistently lower with the ST-Genesia

conclusionDespite the broadly similar methodology used by CAT and ST-Genesia

Indexed as

activated protein Cactivated protein C resistanceantiphospholipid syndromeblood coagulation testsystemic lupus erythematosusthrombomodulin

Identifiers

PMID35011808
PMCPMC8745056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.