ArticleJournal of clinical medicine2021
Plastic Bronchitis-A Serious Rare Complication Affecting Children Only after Fontan Procedure?
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A nomogram model for predicting the risk factors of plastic bronchitis in children.Frontiers in medicine · 2026Article
- Pediatrics advances in 2024: choices in allergy, cardiology, critical care, endocrinology, gastroenterology, immunology, infectious diseases, neonatology, nephrology, neurology, nutrition, palliative care respiratory tract illnesses, and social media.Italian journal of pediatrics · 2025Review
- Characteristics of plastic bronchitis in children with infectious pneumonia.Italian journal of pediatrics · 2025Article
- Pediatric plastic bronchitis associated with smoke inhalation and influenza A: case report and literature review.BMC pulmonary medicine · 2024Review
- Clinical features of plastic bronchitis in children after congenital heart surgery.Italian journal of pediatrics · 2024Article
- Risk factors for pleural effusion in children with plastic bronchitis caused by pneumonia.Frontiers in pediatrics · 2024Article
- Plastic Bronchitis in a Child With Fontan Physiology After COVID-19 Infection.CJC pediatric and congenital heart disease · 2023Article
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6 authors.
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Abstract
backgroundPlastic bronchitis (PB) may occur not only in children following palliative Fontan procedure but also in those without underlying heart disease. We aim to assess the clinical course, therapeutic measures, outcome, and follow-up of PB in children with congenital heart disease (CHD) and children without cardiac problems.
methodsThis retrospective case series assessed children with PB admitted to hospital between 2015 and 2019. Parents or guardians of patients were contacted by e-mail or telephone between September 2017 and June 2019 to enquiry about recurrence of PB and strategy of treatment. The diagnosis of PB was based on the expectoration (spontaneous or during bronchoscopy) of endobronchial plugs.
resultsThis study delineated the clinical, histological, and laboratory features of plastic bronchitis in children following Fontan procedure (Group A) and in those without heart defects (Group B, non-CHD children). The main symptoms were cough accompanied by dyspnea, and hypoxemia with a decrease in oxygen saturation, often leading to acute respiratory failure. In children with CHD, the first episode of PB occurred at a relatively young age. Although chronic, i.e., lasting more than 3 weeks, inhaled therapy was implemented in both groups of patients, the recurrences of PB were observed. The mean time to PB recurrence after the first episode in Group A was longer than that in Group B (1.47 vs. 0.265 years,
conclusionsDespite many similarities, clinical, histological, and laboratory studies in the children with plastic bronchitis after Fontan's surgery and in children without heart defects suggest that there are differences in the course of the disease in patients without CHD, such as a more advanced age of the first episode of PB, the location of plastic casts on the left side, and a stronger role of inflammatory factors and mechanisms. Further research is needed to understand the pathophysiology of PB and choose the most appropriate therapy.
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