Evidence map›Paper›PMID 35011769›Full record

ArticleJournal of clinical medicine2021

Association of COVID-19 with Intracranial Hemorrhage during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A 10-Year Retrospective Observational Study.

Tobias Pantel, Kevin Roedl, Dominik Jarczak, Yuanyuan Yu, Daniel Peter Frings, Barbara Sensen, Hans Pinnschmidt, Alexander Bernhardt, Bastian Cheng, Iris Lettow and 4 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tobias PantelDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Kevin RoedlDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-0721-9027
Dominik JarczakDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-0480-2089
Yuanyuan YuDepartment of Anesthesiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Daniel Peter FringsDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Barbara SensenDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Hans PinnschmidtInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Alexander BernhardtDepartment for Cardiovascular Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Bastian ChengDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-2434-1822
Iris LettowDepartment of Neurology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Manfred WestphalDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Patrick CzorlichDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-0865-241X
Stefan KlugeDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Marlene FischerDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-7530-8155

Funding

Johanna und Fritz Buch Gedächtnis-Stiftung none
6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) is potentially lifesaving for patients with acute respiratory distress syndrome (ARDS) but may be accompanied by serious adverse events, including intracranial hemorrhage (ICRH). We hypothesized that ICRH occurs more frequently in patients with COVID-19 than in patients with ARDS of other etiologies. We performed a single-center retrospective analysis of adult patients treated with venovenous (vv-) ECMO for ARDS between January 2011 and April 2021. Patients were included if they had received a cranial computed tomography (cCT) scan during vv-ECMO support or within 72 h after ECMO removal. Cox regression analysis was used to identify factors associated with ICRH. During the study period, we identified 204 patients with vv-ECMO for ARDS, for whom a cCT scan was available. We observed ICRH in 35.4% (

Indexed as

acute respiratory distress syndromeCOVID-19extracorporeal membrane oxygenationhemorrhagic strokeintracerebral hemorrhageneurologic complications

Identifiers

PMID35011769
PMCPMC8745037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.