Evidence map›Paper›PMID 35011713›Full record

ArticleCells2022

Characterization of Oxygen Levels in an Uninfected and Infected Human Blood-Cerebrospinal-Fluid-Barrier Model.

Alexander Martens, Nicole de Buhr, Hiroshi Ishikawa, Horst Schroten, Maren von Köckritz-Blickwede

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Analysis of the Role of Vasa Vasorum in the Oxygen Transport to the Aneurysm Wall.International journal for numerical methods in biomedical engineering · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Alexander MartensDepartment of Biochemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Nicole de BuhrDepartment of Biochemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-4516-7838
Hiroshi IshikawaLaboratory of Clinical Regenerative Medicine, Department of Neurosurgery, University of Tsukuba, Tsukuba-City, Inaraki 305-8575, Japan.ORCID 0000-0002-7312-0682
Horst SchrotenDepartment of Pediatrics, Pediatric Infectious Diseases, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Maren von Köckritz-BlickwedeDepartment of Biochemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0001-7712-9767
University of Veterinary Medicine Hannover, Foundation · DEHeidelberg University · DEUniversity of Tsukuba · JP

Funding

Ministry of Science and Culture of Lower Saxony Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)
6 · The paper itself

Abstract

The host-pathogen interaction during meningitis can be investigated with blood-cerebrospinal-fluid-barrier (BCSFB) cell culture models. They are commonly handled under atmospheric oxygen conditions (19-21% O

Indexed as

Blood-Brain BarrierCell Culture TechniquesCerebrospinal FluidHumansOxygenStreptococcal InfectionsOxygenblood-cerebrospinal-fluid-barrier (BCSFB)hypoxiameningitisneutrophilsoxygenphysioxiaStreptococcus suis

Identifiers

PMID35011713
PMCPMC8750020
OpenAlexW4205224075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.