Evidence map›Paper›PMID 35011691›Full record

ArticleCells2021

Concetta De Filippis, Barbara Napoli, Laura Rigon, Giulia Guarato, Reinhard Bauer, Rosella Tomanin, Genny Orso

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Concetta De FilippisLaboratory of Diagnosis and Therapy of Lysosomal Disorders, Department of Women's and Children's Health, University of Padova, Via Giustiniani 3, 35128 Padova, Italy.ORCID 0000-0002-9001-1007
Barbara NapoliLaboratory of Molecular Biology, Scientific Institute, IRCCS Eugenio Medea, Via Don Luigi Monza 20, Bosisio Parini, 23842 Lecco, Italy.
Laura RigonFondazione Istituto di Ricerca Pediatrica "Città della Speranza", Corso Stati Uniti 4, 35127 Padova, Italy.
Giulia GuaratoDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.ORCID 0000-0003-2134-4649
Reinhard BauerMolecular Developmental Biology Unit, Life & Medical Sciences Institute (LIMES), University of Bonn, Carl-Troll-Straße 31, 53115 Bonn, Germany.
Rosella TomaninLaboratory of Diagnosis and Therapy of Lysosomal Disorders, Department of Women's and Children's Health, University of Padova, Via Giustiniani 3, 35128 Padova, Italy.ORCID 0000-0002-3346-9900
Genny OrsoDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
University of Padua · ITCittà della Speranza Foundation · ITIRCCS Eugenio Medea · ITUniversity of Bonn · DE

Funding

Fondazione Istituto di Ricerca Pediatrica 'Città della Speranza' 19/05University of Padua SID-018
6 · The paper itself

Abstract

Deficit of the IDUA (α-L-iduronidase) enzyme causes the lysosomal storage disorder mucopolysaccharidosis type I (MPS I), a rare pediatric neurometabolic disease, due to pathological variants in the

Indexed as

Amino Acid SequenceAnimalsAutophagosomesAutophagyDisease Models, AnimalDown-RegulationDrosophila melanogasterDrosophila ProteinsGenes, EssentialGlycolysisLipogenesisLocomotionLongevityLysosomesMucopolysaccharidosis IMusclesDrosophila ProteinsD-iduaDrosophila melanogasterfly modelsHurler syndromeIDUAlysosomal storage disordersMPS Imucopolysaccharidosis type IRNAi

Identifiers

PMID35011691
PMCPMC8750945
OpenAlexW4206174728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.