Evidence map›Paper›PMID 35011623›Full record

ArticleCells2021

Shift in G

Fanghua Li, Emil Mladenov, Rositsa Dueva, Martin Stuschke, Beate Timmermann, George Iliakis

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A perspective on tumor radiation resistance following high-LET radiation treatment.Journal of cancer research and clinical oncology · 2024
    Review
  5. Key molecular DNA damage responses of human cells to radiation.Frontiers in cell and developmental biology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Fanghua LiInstitute of Medical Radiation Biology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0001-7610-8489
Emil MladenovInstitute of Medical Radiation Biology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Rositsa DuevaInstitute of Medical Radiation Biology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Martin StuschkeDivision of Experimental Radiation Biology, Department of Radiation Therapy, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Beate TimmermannDepartment of Particle Therapy, University Hospital Essen, West German Proton Therapy Centre Essen (WPE), West German Cancer Center (WTZ), German Cancer Consortium (DKTK), 45147 Essen, Germany.
George IliakisInstitute of Medical Radiation Biology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
University of Duisburg-Essen · DEGerman Cancer Research Center · DEDeutschen Konsortium für Translationale Krebsforschung · DE

Funding

Deutsche Forschungsgemeinschaft GRK1739Federal Ministry of Education and Research 02S8254, 02S8467, 03NUK005C, 02NUK043B
6 · The paper itself

Abstract

The current view of the involvement of PI3-kinases in checkpoint responses after DNA damage is that ATM is the key regulator of G

Indexed as

Radiation, IonizingA549 CellsAtaxia Telangiectasia Mutated ProteinsDNA-Activated Protein KinaseDose-Response Relationship, RadiationG1 PhaseG1 Phase Cell Cycle CheckpointsHumansModels, BiologicalReproducibility of ResultsAtaxia Telangiectasia Mutated ProteinsATM protein, humanATR protein, humanDNA-Activated Protein KinasePRKDC protein, humanATMATRcell cyclecheckpointsDNA double-strand breaksDNA end resectionDNA-PKcsionizing radiation

Identifiers

PMID35011623
PMCPMC8750242
OpenAlexW4200610552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.