Evidence map›Paper›PMID 35011611›Full record

ArticleCells2021

Altered Ca

Ralfs Buks, Tracy Dagher, Maria Giustina Rotordam, David Monedero Alonso, Sylvie Cochet, Emilie-Fleur Gautier, Philippe Chafey, Bruno Cassinat, Jean-Jacques Kiladjian, Nadine Becker and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Red Blood Cell Morphodynamics in Patients with Polycythemia Vera and Stroke.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Ralfs BuksBIGR, UMR_S1134, Inserm, Université de Paris, F-75015 Paris, France.ORCID 0000-0002-0282-4500
Tracy DagherLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.
Maria Giustina RotordamNanion Technologies GmbH, 80339 Munich, Germany.
David Monedero AlonsoLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.
Sylvie CochetBIGR, UMR_S1134, Inserm, Université de Paris, F-75015 Paris, France.
Emilie-Fleur GautierLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.ORCID 0000-0002-0394-6606
Philippe ChafeyProteomics Platform 3P5, Université de Paris, Institut Cochin, INSERM, U1016, CNRS, UMR8104 Paris, France.
Bruno CassinatLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.
Jean-Jacques KiladjianLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.ORCID 0000-0002-8121-438X
Nadine BeckerNanion Technologies GmbH, 80339 Munich, Germany.
Isabelle PloLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.ORCID 0000-0002-5915-6910
Stéphane EgéeLaboratoire d'Excellence GR-Ex, F-75015 Paris, France.
Wassim El NemerBIGR, UMR_S1134, Inserm, Université de Paris, F-75015 Paris, France.ORCID 0000-0001-8184-427X
Inserm · FRCentre National de la Recherche Scientifique · FRNanion (Germany) · DE

Funding

Agence Nationale de la Recherche ANR-11-IDEX-0005-02Agence Nationale de la Recherche ANR-11-LABX-0051Agence Nationale de la Recherche ANR-18-IDEX-0001European Union European Union's Horizon 2020 Research and Innovation Program
6 · The paper itself

Abstract

Over 95% of Polycythemia Vera (PV) patients carry the V617F mutation in the tyrosine kinase Janus kinase 2 (JAK2), resulting in uncontrolled erythroid proliferation and a high risk of thrombosis. Using mass spectrometry, we analyzed the RBC membrane proteome and showed elevated levels of multiple Ca

Indexed as

ErythropoiesisHomeostasisAnimalsCalciumCell SizeErythroblastsErythrocytesErythroid CellsHumansIntermediate-Conductance Calcium-Activated Potassium ChannelsIntracellular SpaceJanus Kinase 2MiceMice, Inbred C57BLMutationOrganellesCalciumIntermediate-Conductance Calcium-Activated Potassium ChannelsJAK2 protein, humanJanus Kinase 2KCNN4 protein, humanProteomeCa2+enucleationJAK2V617Forganelle sortingpolycythemia verared blood cellsreticulocytes

Identifiers

PMID35011611
PMCPMC8750512
OpenAlexW4200049212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.