Evidence map›Paper›PMID 35011600›Full record

ReviewCells2021

Genetic Control of MAP3K1 in Eye Development and Sex Differentiation.

Jingjing Wang, Eiki Kimura, Maureen Mongan, Ying Xia

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jingjing WangDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH 45267-0056, USA.
Eiki KimuraDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH 45267-0056, USA.ORCID 0000-0001-7164-8099
Maureen MonganDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH 45267-0056, USA.
Ying XiaDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH 45267-0056, USA.ORCID 0000-0001-9532-9527
University of Cincinnati Medical Center · US

Funding

The Role of MAP 3 Kinase 1 in Ocular Surface MorphogenesisR01EY015227 · NEI · UNIVERSITY OF CINCINNATI · PI XIA, YING · 2004 to 2019
$5.4M
Gene-environment interactions in epithelial morphogenesisR01HD098106 · NICHD · UNIVERSITY OF CINCINNATI · PI XIA, YING · 2019 to 2023
$2.3M
NEI NIH HHS R01 EY015227NICHD NIH HHS R01 HD098106
6 · The paper itself

Abstract

The MAP3K1 is responsible for transmitting signals to activate specific MAP2K-MAPK cascades. Following the initial biochemical characterization, genetic mouse models have taken center stage to elucidate how MAP3K1 regulates biological functions. To that end, mice were generated with the ablation of the entire

Indexed as

AnimalsEmbryonic DevelopmentGene-Environment InteractionGene Expression Regulation, DevelopmentalHumansMAP Kinase Kinase Kinase 1MiceSex DifferentiationMap3k1 protein, mouseMAP Kinase Kinase Kinase 1dioxinembryonic eyelid closuregene-environment interactionsgenetic crosstalksJNKMAP3K1sex development and differentiation

Identifiers

PMID35011600
PMCPMC8750206
OpenAlexW4200484934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.