Evidence map›Paper›PMID 35011595›Full record

ReviewCells2021

Bacterial Lymphatic Metastasis in Infection and Immunity.

Matthew K Siggins, Shiranee Sriskandan

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. ASM case reports · 2025
    Article
  12. Revealing the impact ofFrontiers in immunology · 2025
    Article
  13. Tumor-ColonizingBiomolecules · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew K SigginsNational Heart and Lung Institute, Imperial College London, London W2 1PG, UK.ORCID 0000-0003-2504-6518
Shiranee SriskandanDepartment of Infectious Disease, Imperial College London, London W12 0NN, UK.ORCID 0000-0002-5214-4941
Imperial College London · GB

Funding

Medical Research Council MC_PC_19040Medical Research Council MR/L008610/1Medical Research Council MR/R005974/1
6 · The paper itself

Abstract

Lymphatic vessels permeate tissues around the body, returning fluid from interstitial spaces back to the blood after passage through the lymph nodes, which are important sites for adaptive responses to all types of pathogens. Involvement of the lymphatics in the pathogenesis of bacterial infections is not well studied. Despite offering an obvious conduit for pathogen spread, the lymphatic system has long been regarded to bar the onward progression of most bacteria. There is little direct data on live virulent bacteria, instead understanding is largely inferred from studies investigating immune responses to viruses or antigens in lymph nodes. Recently, we have demonstrated that extracellular bacterial lymphatic metastasis of virulent strains of

Indexed as

ImmunityAnimalsBacterial InfectionsExtracellular MatrixHumansLymphatic MetastasisRheologyVirulencebacteraemiabacteriabacterial disseminationimmunityinfectioninvasionlymphatic metastasislymphaticslymphatic systemlymph nodes

Identifiers

PMID35011595
PMCPMC8750085
OpenAlexW4200301684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.