Evidence map›Paper›PMID 35011513›Full record

ArticleMolecules (Basel, Switzerland)2022

Dual-Responsive Alginate Hydrogel Constructed by Sulfhdryl Dendrimer as an Intelligent System for Drug Delivery.

Li Li, Dongyu Lei, Jiaojiao Zhang, Lu Xu, Jiashan Li, Lu Jin, Le Pan

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Li LiChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.
Dongyu LeiDepartment of Physiology, Preclinical School, Xinjiang Medical University, Urumqi 830011, China.
Jiaojiao ZhangChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.
Lu XuChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.
Jiashan LiChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.
Lu JinChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0000-0001-6513-6206
Le PanChemical Engineering College, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0000-0001-6238-3252
Xinjiang Agricultural University · CNJiangnan University · CNXinjiang Medical University · CN

Funding

National Natural Science Foundation of China 21762043National Natural Science Foundation of China 31960547Natural Science Foundation of Xinjiang Province, China 2019D01B20The Open Project of Key Laboratory of Synthetic and Biological Colloids, Ministry of Education JDSJ2018-07
6 · The paper itself

Abstract

Intelligent stimulus-triggered release and high drug-loading capacity are crucial requirements for drug delivery systems in cancer treatment. Based on the excessive intracellular GSH expression and pH conditions in tumor cells, a novel glutathione (GSH) and pH dual-responsive hydrogel was designed and synthesized by conjugates of glutamic acid-cysteine dendrimer with alginate (

Indexed as

AlginatesAntineoplastic AgentsDendrimersDoxycyclineHydrogelsAnimalsDelayed-Action PreparationsHep G2 CellsHumansMiceNeoplasmsAlginatesAntineoplastic AgentsDelayed-Action PreparationsDendrimersDoxycyclineHydrogelsanti-tumor activitydendrimer modified hydrogelGSH- and pH-responsive

Identifiers

PMID35011513
PMCPMC8746751
OpenAlexW4206521046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.