Evidence map›Paper›PMID 35011479›Full record

ArticleMolecules (Basel, Switzerland)2021

In Vitro Antineoplastic and Antiviral Activity and In Vivo Toxicity of

Maya M Zaharieva, Lyudmila L Dimitrova, Stanislav Philipov, Ivanka Nikolova, Neli Vilhelmova, Petar Grozdanov, Nadya Nikolova, Milena Popova, Vassya Bankova, Spiro M Konstantinov and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Metabolites ofMetabolites · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maya M ZaharievaDepartment of Infectious Microbiology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.
Lyudmila L DimitrovaDepartment of Infectious Microbiology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0002-2577-5625
Stanislav PhilipovDepartment of Human Anatomy, Histology, General and Clinical Pathology and Forensic Medicine, Faculty of Medicine, Sofia University St. Kliment Ohridski, 2 Kozyak Street, 1421 Sofia, Bulgaria.
Ivanka NikolovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.
Neli VilhelmovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.
Petar GrozdanovLaboratory Center Pasteur, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0003-2788-382X
Nadya NikolovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.
Milena PopovaLaboratory Chemistry of Natural Products, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 9 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0002-9296-9059
Vassya BankovaLaboratory Chemistry of Natural Products, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 9 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.ORCID 0000-0002-2417-6313
Spiro M KonstantinovDepartment of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University Sofia, 2 Dunav Street, 1000 Sofia, Bulgaria.
Dimitrina Zheleva-DimitrovaDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University Sofia, 2 Dunav Street, 1000 Sofia, Bulgaria.
Hristo M NajdenskiDepartment of Infectious Microbiology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Street, 1113 Sofia, Bulgaria.

Funding

Bulgarian Academy of Sciences DFNP-70/01.06.2016, DFNP 17-143/01.08.2017
6 · The paper itself

Abstract

This study evaluated the in vitro antineoplastic and antiviral potential and in vivo toxicity of twelve extracts with different polarity obtained from the herbaceous perennial plant

Indexed as

Antineoplastic Agents, PhytogenicAntiviral AgentsCell ProliferationCell SurvivalChromatography, High Pressure LiquidDose-Response Relationship, DrugGeumHEK293 CellsHumansOrgan SpecificityPhytochemicalsPlant ExtractsTandem Mass SpectrometryAntineoplastic Agents, PhytogenicAntiviral AgentsPhytochemicalsPlant Extractsacute in vivo toxicityGeum urbanum L. extractsin vitro antineoplastic and antiviral activityUHPLC–HRMS analysis

Identifiers

PMID35011479
PMCPMC8747043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.