Evidence map›Paper›PMID 35011476›Full record

ArticleMolecules (Basel, Switzerland)2021

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.

Spyridon Dimitrakis, Efthymios-Spyridon Gavriil, Athanasios Pousias, Nikolaos Lougiakis, Panagiotis Marakos, Nicole Pouli, Katerina Gioti, Roxane Tenta

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Spyridon DimitrakisDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Efthymios-Spyridon GavriilDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Athanasios PousiasDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Nikolaos LougiakisDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.ORCID 0000-0003-0582-4415
Panagiotis MarakosDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Nicole PouliDepartment of Pharmacy, Division of Pharmaceutical Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Katerina GiotiDepartment of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.
Roxane TentaDepartment of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.ORCID 0000-0002-4867-6945
National and Kapodistrian University of Athens · GRHarokopio University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of pyrrolo[2,3-

Indexed as

Chemistry Techniques, SyntheticAntineoplastic AgentsCell CycleCell Line, TumorCell ProliferationDose-Response Relationship, DrugFibroblastsHumansMolecular StructurePyrimidinesStructure-Activity RelationshipAntineoplastic AgentsPyrimidinesapoptosiscell cycle perturbationcytotoxic activitypurine isosterespyrazolopyrimidinepyrrolopyridinepyrrolopyrimidinesynthesis

Identifiers

PMID35011476
PMCPMC8746528
OpenAlexW4205638498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.