Evidence map›Paper›PMID 35011470›Full record

ArticleMolecules (Basel, Switzerland)2021

The Immuno-Modulatory Activities of Pentaherbs Formula on Ovalbumin-Induced Allergic Rhinitis Mice via the Activation of Th1 and Treg Cells and Inhibition of Th2 and Th17 Cells.

Peiting Li, Miranda Sin-Man Tsang, Lea Ling-Yu Kan, Tianheng Hou, Sharon Sze-Man Hon, Ben Chung-Lap Chan, Ida Miu-Ting Chu, Christopher Wai-Kei Lam, Ping-Chung Leung, Chun-Kwok Wong

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in pharmacology · 2026
    Article
  4. Article
  5. Article
  6. [Adipose-derived stem cell-derived exosomes regulate Th2/Treg balance in peripheral blood of AR patients through the mTOR pathway].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
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  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Peiting LiState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Miranda Sin-Man TsangState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Lea Ling-Yu KanState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Tianheng HouDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.ORCID 0000-0003-1946-1635
Sharon Sze-Man HonState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Ben Chung-Lap ChanState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-5505-1065
Ida Miu-Ting ChuDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
Christopher Wai-Kei LamFaculty of Medicine and State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Ping-Chung LeungState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0195-4688
Chun-Kwok WongState Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-5637-8331
Chinese University of Hong Kong · HKMacau University of Science and Technology · MOUniversity of California, Los Angeles · US

Funding

Innovation and Technology Commission, Hong Kong 00000Li Dak Sum Yip Yio Chin R & D Centre for Chinese Medicine, CUHK, Hong Kong 00000
6 · The paper itself

Abstract

Allergic rhinitis (AR) is a highly prevalent allergic disease induced by immunoglobulin (Ig) E-mediated hypersensitivity reaction at the nasal epithelium against inhaled allergens. Previous studies have demonstrated that Pentaherbs formula (PHF), a modified herbal formula comprising five herbal medicines (

Indexed as

AllergensAnimalsAnti-Inflammatory AgentsCytokinesDisease Models, AnimalHerbal MedicineImmunologic FactorsImmunomodulationLymphocyte ActivationMiceNasal Lavage FluidNasal MucosaOvalbuminPlant ExtractsPlants, MedicinalRhinitis, AllergicAllergensAnti-Inflammatory AgentsCytokinesImmunologic FactorsOvalbuminPlant Extractsallergic rhinitiscytokinesnasal epitheliumPentaherbs formulaT cells

Identifiers

PMID35011470
PMCPMC8746371
OpenAlexW4205354867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.