Evidence map›Paper›PMID 35011457›Full record

ReviewMolecules (Basel, Switzerland)2021

Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents.

Juveriya Farooq, Rokeya Sultana, Tahreen Taj, Syed Mohammed Basheeruddin Asdaq, Abdulkhaliq J Alsalman, Mohammed Al Mohaini, Maitham A Al Hawaj, Mehnaz Kamal, Saad Alghamdi, Mohd Imran and 2 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Involvement of Nrf2, JAK and COX pathways in acetaminophen-induced nephropathy: Role of some antioxidants.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  11. 3 Biotech · 2023
    Article
  12. Article
  13. The Potential Role ofMolecules (Basel, Switzerland) · 2022
    Article
  14. Molecules (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juveriya FarooqDepartment of Pharmacology, Yenepoya Pharmacy College and Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0002-6981-3689
Rokeya SultanaDepartment of Pharmacognosy, Yenepoya Pharmacy College and Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.
Tahreen TajDepartment of Pharmacology, Yenepoya Pharmacy College and Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.
Syed Mohammed Basheeruddin AsdaqDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia.ORCID 0000-0003-1533-9667
Abdulkhaliq J AlsalmanDepartment of Clinical Pharmacy, Faculty of Pharmacy, Northern Border University, Arar 91911, Saudi Arabia.
Mohammed Al MohainiBasic Sciences Department, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 31982, Saudi Arabia.ORCID 0000-0002-0185-4484
Maitham A Al HawajDepartment of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Mehnaz KamalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0002-3585-0828
Saad AlghamdiLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia.ORCID 0000-0003-4532-9128
Mohd ImranDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Arar 91911, Saudi Arabia.ORCID 0000-0002-6064-1040
Haleema ShahinDepartment of Pharmacology, Yenepoya Pharmacy College and Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0002-2538-6654
Ruheena TabassumDepartment of Pharmacology, Yenepoya Pharmacy College and Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.ORCID 0000-0002-2540-8024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The drugs used to treat cancer not only kill fast-growing cancer cells, but also kill or slow the growth of healthy cells, causing systemic toxicities that lead to altered functioning of normal cells. Most chemotherapeutic agents have serious toxicities associated with their use, necessitating extreme caution and attention. There is a growing interest in herbal remedies because of their pharmacological activities, minimal side effects, and low cost. Thymoquinone, a major component of the volatile oil of

Indexed as

Antineoplastic AgentsAntioxidantsBenzoquinonesHumansNigella sativaOils, VolatileOxidative StressPhytochemicalsPlant ExtractsProtective AgentsStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsBenzoquinonesOils, VolatilePhytochemicalsPlant ExtractsProtective Agentsthymoquinoneantioxidantchemotherapy-induced toxicityorgan protectionphytoconstituentsthymoquinone

Identifiers

PMID35011457
PMCPMC8746502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.