Evidence map›Paper›PMID 35011447›Full record

ReviewMolecules (Basel, Switzerland)2021

Identification and Quantification, Metabolism and Pharmacokinetics, Pharmacological Activities, and Botanical Preparations of Protopine: A Review.

Wangli Huang, Lingbo Kong, Yang Cao, Liang Yan

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Design, Synthesis, SwissADME Profile DFT Studies,Current medicinal chemistry · 2026
    Article
  5. Review
  6. Plants (Basel, Switzerland) · 2025
    Review
  7. Antitumor Alkaloids in Tibetan Corydalis: Chemical Diversity and Pharmacological Insights.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  8. Metabolites from thePharmaceuticals (Basel, Switzerland) · 2025
    Article
  9. Bioactivity of Synthesized Trifluoromethyl Thioxanthone Analogues.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Veterinary medicine international · 2024
    Article
  15. Review
  16. Safety and efficacy of a feed additive consisting ofEFSA journal. European Food Safety Authority · 2023
    Article
  17. A Study of the Chemical Composition and Biological Activity ofInternational journal of molecular sciences · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wangli HuangDepartment of Spine, Honghui-Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710054, China.
Lingbo KongDepartment of Spine, Honghui-Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710054, China.
Yang CaoDepartment of Spine, Honghui-Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710054, China.
Liang YanDepartment of Spine, Honghui-Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710054, China.
Xi'an Jiaotong University · CNXi'an Honghui Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through pharmacological activity research, an increasing number of natural products and their derivatives are being recognized for their therapeutic value. In recent years, studies have been conducted on

Indexed as

Anti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBenzophenanthridinesBerberine AlkaloidsBiological ProductsDrugs, Chinese HerbalEnzyme InhibitorsHumansMetabolic Networks and PathwaysMolecular StructurePlatelet Aggregation InhibitorsSpectrum AnalysisStructure-Activity RelationshipAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBenzophenanthridinesBerberine AlkaloidsBiological ProductsDrugs, Chinese HerbalEnzyme InhibitorsPlatelet Aggregation Inhibitorsprotopinenatural productspharmacological activitiesprotopine

Identifiers

PMID35011447
PMCPMC8746401
OpenAlexW4206469243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.