Evidence map›Paper›PMID 35011383›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, Pharmacological Evaluation, and Computational Studies of Cyclic Opioid Peptidomimetics Containing β

Karol Wtorek, Piotr F J Lipiński, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Jarosław Sukiennik, Alicja Kluczyk, Anna Janecka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Karol WtorekDepartment of Biomolecular Chemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.ORCID 0000-0002-3567-6962
Piotr F J LipińskiDepartment of Neuropeptides, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.ORCID 0000-0002-8364-7955
Anna Adamska-BartłomiejczykDepartment of Biomolecular Chemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
Justyna Piekielna-CiesielskaDepartment of Biomolecular Chemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
Jarosław SukiennikTriMen Chemicals Ltd., 92-318 Lodz, Poland.
Alicja KluczykFaculty of Chemistry, University of Wroclaw, 50-383 Wroclaw, Poland.ORCID 0000-0003-2943-2782
Anna JaneckaDepartment of Biomolecular Chemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland.
Medical University of Lodz · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PLSanten (Japan) · JPUniversity of Wrocław · PL

Funding

Medical University of Lodz 503/1-156-02/503-11-001-19-00
6 · The paper itself

Abstract

Our formerly described pentapeptide opioid analog Tyr-c[D-Lys-Phe-Phe-Asp]NH

Indexed as

Models, MolecularAnalgesics, OpioidAnimalsBinding SitesCell LineChemistry Techniques, SyntheticChromatography, LiquidHumansLysineMass SpectrometryMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructurePeptides, CyclicPeptidomimeticsProtein BindingAnalgesics, OpioidLysinePeptides, CyclicPeptidomimeticsReceptors, Opioidfunctional assayopioid receptorspeptide synthesisreceptor binding studiesβ-amino acids

Identifiers

PMID35011383
PMCPMC8747000
OpenAlexW4200484321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.