Evidence map›Paper›PMID 35011380›Full record

ReviewMolecules (Basel, Switzerland)2021

Metal Complexes or Chelators with ROS Regulation Capacity: Promising Candidates for Cancer Treatment.

Xiang Li, Yuhui Wang, Man Li, Huipeng Wang, Xiongwei Dong

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Early Transition Metal-Based Antitumor Complexes.Chemistry, an Asian journal · 2026
    Review
  2. Review
  3. Review
  4. Effects of pollen patties with curcumin-steviol glycoside complex onJournal of animal science and technology · 2025
    Article
  5. Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N'-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  6. Article
  7. Article
  8. Silver(I) 1,10-Phenanthroline Complexes Are Active againstJournal of fungi (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiang LiCollege of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Yuhui WangSchool of Chemistry, Central China Normal University, Wuhan 430079, China.
Man LiSchool of Chemistry, Central China Normal University, Wuhan 430079, China.
Huipeng WangNational Local Joint Engineering Laboratory for Advanced Textile Processing and Clean Production, Wuhan Textile University, Wuhan 430073, China.
Xiongwei DongNational Local Joint Engineering Laboratory for Advanced Textile Processing and Clean Production, Wuhan Textile University, Wuhan 430073, China.
Central China Normal University · CNWuhan Textile University · CNPeking University · CN

Funding

Educational Commission of Hubei Province of China Q20171601Hubei Provincial Natural Science Foundation of China 2017CFB206National Natural Science Foundation of China 21701128
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are rapidly eliminated and reproduced in organisms, and they always play important roles in various biological functions and abnormal pathological processes. Evaluated ROS have frequently been observed in various cancers to activate multiple pro-tumorigenic signaling pathways and induce the survival and proliferation of cancer cells. Hydrogen peroxide (H

Indexed as

AnimalsAntineoplastic AgentsChelating AgentsCoordination ComplexesEnzyme InhibitorsHumansMitochondriaNeoplasmsReactive Oxygen SpeciesSuperoxide DismutaseAntineoplastic AgentsChelating AgentsCoordination ComplexesEnzyme InhibitorsReactive Oxygen SpeciesSuperoxide Dismutaseanti-cancerantioxidant enzymeschelatorsmetal complexesmitochondriareactive oxygen speciesSOD1TrxR

Identifiers

PMID35011380
PMCPMC8746559
OpenAlexW4206009009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.