Evidence map›Paper›PMID 35011378›Full record

ArticleMolecules (Basel, Switzerland)2021

Folding and Unfolding of Exogenous G-Rich Oligonucleotides in Live Cells by Fluorescence Lifetime Imaging Microscopy of

Ting-Yuan Tseng, Chiung-Lin Wang, Wei-Chun Huang, Ta-Chau Chang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ting-Yuan TsengInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan.
Chiung-Lin WangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan.
Wei-Chun HuangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan.
Ta-Chau ChangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan.
Institute of Atomic and Molecular Sciences, Academia Sinica · TW

Funding

the Ministry of Science and Technology of the Republic of China MOST-109-2113-M-001-028
6 · The paper itself

Abstract

Guanine-rich oligonucleotides (GROs) can self-associate to form G-quadruplex (G4) structures that have been extensively studied in vitro. To translate the G4 study from in vitro to in live cells, here fluorescence lifetime imaging microscopy (FLIM) of an

Indexed as

G-QuadruplexesCarbazolesCell Line, TumorFluorescent DyesHumansLysosomesMicroscopy, FluorescenceOligonucleotidesPyridinium Compounds3,6-bis(1-methyl-2-vinylpyridinium)carbazoleCarbazolesFluorescent DyesOligonucleotidesPyridinium Compoundsfluorescence lifetime imaging microscopyG4 dynamics in live cellso-BMVC fluorescent probe

Identifiers

PMID35011378
PMCPMC8747072
OpenAlexW4200272142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.