ReviewMolecules (Basel, Switzerland)2021
Catalytic Approaches to Multicomponent Reactions: A Critical Review and Perspectives on the Roles of Catalysis.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- Solvent-Controlled Reaction Productivity and Mechanistic Pathways in the Multicomponent Synthesis of 2‑Amino-3-cyano‑4ACS organic & inorganic Au · 2026Article
- Facile synthesis ofRSC advances · 2026Article
- Micellar effects upon synthesis of 1,2-dihydro-1-arylnaphtho[1,2-RSC advances · 2026Article
- Synergistic Catalysis: Integrating Acids, Metals, and Light in Nature-Inspired Asymmetric Multicomponent Synthesis.Topics in current chemistry (Cham) · 2026Review
- RHA/TiOScientific reports · 2026Article
- Article
- Nanomagnetic 4-amino-3-hydroxynaphthalene-1-sulfonic as an efficient heterogeneous catalyst for multicomponent synthesis of 2-amino-3-cyano-4,6-diarylpyridines under green conditions.Scientific reports · 2025Article
- Magnetically recoverable catalysts for efficient multicomponent synthesis of organosulfur compounds.RSC advances · 2025Review
- Design of an efficient magnetic brush solid acid and its catalytic use in organic reactions.Scientific reports · 2025Article
- Selective Ni(I)/Ni(III) Process for Consecutive Geminal C(spJournal of the American Chemical Society · 2024Article
- PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo-rescence Microscopy.Angewandte Chemie (International ed. in English) · 2024Article
- Article
- Engaging Isatins and Amino Acids in Multicomponent One-Pot 1,3-Dipolar Cycloaddition Reactions-Easy Access to Structural Diversity.Molecules (Basel, Switzerland) · 2023Review
- Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1,4-benzodiazepines.Nanoscale advances · 2023Article
- Ugi Four-Component Reactions Using Alternative Reactants.Molecules (Basel, Switzerland) · 2023Review
- In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates.Molecules (Basel, Switzerland) · 2022Review
- 3-(Propylthio)propane-1-sulfonic acid immobilized on functionalized magnetic nanoparticles as an efficient catalyst for one-pot synthesis of dihydrotetrazolo[1,5-RSC advances · 2022Article
- 1-Aminoalkylphosphonium Derivatives: Smart Synthetic Equivalents ofMolecules (Basel, Switzerland) · 2022Review
- Hf(OTf)Molecules (Basel, Switzerland) · 2022Article
- Synthesis and characterization of new 1,4-dihydropyran derivatives by novel Ta-MOF nanostructures as reusable nanocatalyst with antimicrobial activity.Frontiers in chemistry · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In this review, we comprehensively describe catalyzed multicomponent reactions (MCRs) and the multiple roles of catalysis combined with key parameters to perform these transformations. Besides improving yields and shortening reaction times, catalysis is vital to achieving greener protocols and to furthering the MCR field of research. Considering that MCRs typically have two or more possible reaction pathways to explain the transformation, catalysis is essential for selecting a reaction route and avoiding byproduct formation. Key parameters, such as temperature, catalyst amounts and reagent quantities, were analyzed. Solvent effects, which are likely the most neglected topic in MCRs, as well as their combined roles with catalysis, are critically discussed. Stereocontrolled MCRs, rarely observed without the presence of a catalytic system, are also presented and discussed in this review. Perspectives on the use of catalytic systems for improved and greener MCRs are finally presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.