Evidence map›Paper›PMID 35011190›Full record

ArticleAnimals : an open access journal from MDPI2021

Identification of Monoallelically Expressed Genes Associated with Economic Traits in Hanwoo (Korean Native Cattle).

Kyu-Sang Lim, Hyung-Chul Kim, Bong-Hwan Choi, Ju-Whan Son, Kyung-Tai Lee, Tae-Jeong Choi, Yong-Min Cho, Han-Ha Chai, Jong-Eun Park, Woncheoul Park and 3 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kyu-Sang LimDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-5406-266X
Hyung-Chul KimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.
Bong-Hwan ChoiAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.
Ju-Whan SonAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.
Kyung-Tai LeeAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.ORCID 0000-0003-0990-4818
Tae-Jeong ChoiAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.ORCID 0000-0002-8299-9342
Yong-Min ChoAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.
Han-Ha ChaiAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.ORCID 0000-0001-7752-3967
Jong-Eun ParkAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.ORCID 0000-0003-0718-3463
Woncheoul ParkAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.
Chiwoong LimDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Gyeonggi-do, Korea.
Jun-Mo KimDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Gyeonggi-do, Korea.ORCID 0000-0002-6934-398X
Dajeong LimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju 55365, Jeollabuk-do, Korea.ORCID 0000-0003-3966-9150

Funding

Rural Development Administration PJ01098002
6 · The paper itself

Abstract

Hanwoo, an indigenous Korean cattle breed, has been genetically improved by selecting superior sires called Korean-proven bulls. However, cows still contribute half of the genetic stock of their offspring, and allelic-specific expressed genes have potential, as selective targets of cows, to enhance genetic gain. The aim of this study is to identify genes that have MAEs based on both the genome and transcriptome and to estimate their effects on breeding values (BVs) for economically important traits in Hanwoo. We generated resequencing data for the parents and RNA-sequencing data for the muscle, fat, and brain tissues of the offspring. A total of 3801 heterozygous single nucleotide polymorphisms (SNPs) in offspring were identified and they were located in 1569 genes. Only 14 genes showed MAE (seven expressing maternal alleles and seven expressing paternal alleles). Tissue-specific MAE was observed, and

Indexed as

adult tissuesbreeding valueHanwoomonoallelic expressionpolymorphism

Identifiers

PMID35011190
PMCPMC8749587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.