Evidence map›Paper›PMID 35011183›Full record

ArticleAnimals : an open access journal from MDPI2021

Measurement of Plasma Resistin Concentrations in Horses with Metabolic and Inflammatory Disorders.

Beatriz Fuentes-Romero, Alberto Muñoz-Prieto, José J Cerón, María Martín-Cuervo, Manuel Iglesias-García, Escolástico Aguilera-Tejero, Elisa Díez-Castro

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beatriz Fuentes-RomeroDepartment of Equine Internal Medicine, University of Extremadura, 10004 Cáceres, Spain.ORCID 0000-0002-2788-3259
Alberto Muñoz-PrietoInterdisciplinary Laboratory of Clinical Pathology, Interlab-UMU, University of Murcia, 30003 Murcia, Spain.ORCID 0000-0001-6865-8712
José J CerónInterdisciplinary Laboratory of Clinical Pathology, Interlab-UMU, University of Murcia, 30003 Murcia, Spain.
María Martín-CuervoDepartment of Equine Internal Medicine, University of Extremadura, 10004 Cáceres, Spain.ORCID 0000-0002-4169-5318
Manuel Iglesias-GarcíaDepartment of Equine Surgery, University of Extremadura, 10004 Cáceres, Spain.
Escolástico Aguilera-TejeroDepartment of Equine Internal Medicine, University of Córdoba, 14014 Córdoba, Spain.
Elisa Díez-CastroDepartment of Equine Internal Medicine, University of Córdoba, 14014 Córdoba, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and its associated complications, such as metabolic syndrome, are an increasing problem in both humans and horses in the developed world. The expression patterns of resistin differ considerably between species. In rodents, resistin is expressed by adipocytes and is related to obesity and ID. In humans, resistin is predominantly produced by inflammatory cells, and resistin concentrations do not reflect the degree of obesity, although they may predict cardiovascular outcomes. The aim of this study was to investigate the usefulness of resistin and its relationship with ID and selected indicators of inflammation in horses. Seventy-two horses, included in one of the four following groups, were studied: healthy controls (C, n = 14), horses with inflammatory conditions (I, n = 21), horses with mild ID (ID1, n = 18), and horses with severe ID (ID2, n = 19). Plasma resistin concentrations were significantly different between groups and the higher values were recorded in the I and ID2 groups (C: 2.38 ± 1.69 ng/mL; I: 6.85 ± 8.38 ng/mL; ID1: 2.41 ± 2.70 ng/mL; ID2: 4.49 ± 3.08 ng/mL). Plasma resistin was not correlated with basal insulin concentrations. A significant (r = 0.336,

Indexed as

adipokineinflammationinsulin dysregulationresistin

Identifiers

PMID35011183
PMCPMC8744951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.