Evidence map›Paper›PMID 35011160›Full record

ArticleAnimals : an open access journal from MDPI2021

Drenching Bovine Colostrum, Quercetin or Fructo-Oligosaccharides Has No Effect on Health or Survival of Low Birth Weight Piglets.

Kevin Van Tichelen, Sara Prims, Miriam Ayuso, Céline Van Kerschaver, Mario Vandaele, Jeroen Degroote, Steven Van Cruchten, Joris Michiels, Chris Van Ginneken

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kevin Van TichelenComparative Perinatal Development, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0002-3111-4057
Sara PrimsComparative Perinatal Development, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0001-6577-3563
Miriam AyusoComparative Perinatal Development, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0001-6045-394X
Céline Van KerschaverLaboratory for Animal Production and Animal Product Quality, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.
Mario VandaeleLaboratory for Animal Production and Animal Product Quality, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.
Jeroen DegrooteLaboratory for Animal Production and Animal Product Quality, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.ORCID 0000-0002-8139-8799
Steven Van CruchtenComparative Perinatal Development, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0002-3144-1840
Joris MichielsLaboratory for Animal Production and Animal Product Quality, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.
Chris Van GinnekenComparative Perinatal Development, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0002-1622-9120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of hyperprolific sows has resulted in more low birth weight (LBW) piglets, accompanied by higher mortality. A possible strategy to enhance the resilience and survival of LBW piglets is oral supplementation (drenching) of bioactive substances. This study evaluated the supplementation of bovine colostrum, short-chain fructo-oligosaccharides (scFOS) or quercetin that were dissolved separately in a milk replacer. The study was divided into two sub-experiments. First, the milk replacer was compared with a sham drenched group. Secondly, each dissolved compound was compared with the milk replacer. The LBW piglets, defined as weighing between (mean litter birth weight -1*SD) and (mean litter birth weight -2.5*SD), were randomly allocated to the different treatments and drenched once a day for seven days. On day 1, 3, 9, 24 and 38, piglets were weighed and scored for skin lesions. Blood samples were collected on day 9 and 38 and analyzed to determine glucose, non-esterified fatty acids, urea, immunoglobulin G, insulin-like growth factor 1, and a standard blood panel test. There was no difference between sham drenched piglets and piglets that were drenched with milk replacer regarding any of the parameters. No effect was observed between the milk replacer group and any of the bioactive compounds either, except a higher mortality within the scFOS group. In conclusion, this study showed that drenching the evaluated bioactive compounds, in the used dosages, did not improve LBW piglets' resilience or survival and more research is required to determine the effect of scFOS on small piglets.

Indexed as

colostrumlow birthweightmilk replacerneonataloral supplementationperformancepigquercetinscFOSsurvival

Identifiers

PMID35011160
PMCPMC8749686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.