Evidence map›Paper›PMID 35011106›Full record

Trial reportNutrients2022

Curcumin Supplementation (Meriva

Francesca Pivari, Alessandra Mingione, Giada Piazzini, Camilla Ceccarani, Emerenziana Ottaviano, Caterina Brasacchio, Michele Dei Cas, Margherita Vischi, Mario Gennaro Cozzolino, Paolo Fogagnolo and 8 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 5 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 5 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Pooled it
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Francesca PivariBiochemistry and Molecular Biology Laboratory, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-2277-6833
Alessandra MingioneBiochemistry and Molecular Biology Laboratory, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0001-8008-0191
Giada PiazziniBiochemistry and Molecular Biology Laboratory, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
Camilla CeccaraniInstitute of Biomedical Technologies, Italian National Research Council, 20090 Segrate, Italy.ORCID 0000-0003-3824-7239
Emerenziana OttavianoLaboratory of Microbiology, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0003-3839-2698
Caterina BrasacchioDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
Michele Dei CasClinical Biochemistry and Mass Spectrometry Laboratory, Health Sciences Department, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0001-7359-8558
Margherita VischiNephrology and Dialysis Unit, A.S.S.T. Santi Paolo e Carlo, 20142 Milan, Italy.
Mario Gennaro CozzolinoDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-8494-6252
Paolo FogagnoloDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
Antonella RivaR & D Indena S.p.A, 20139 Milan, Italy.ORCID 0000-0003-2819-943X
Giovanna PetrangoliniR & D Indena S.p.A, 20139 Milan, Italy.ORCID 0000-0001-6681-7329
Luigi BarreaDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, 80131 Naples, Italy.ORCID 0000-0001-9054-456X
Laura Di RenzoSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-8875-6723
Elisa BorghiLaboratory of Microbiology, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-1893-0455
Paola SignorelliBiochemistry and Molecular Biology Laboratory, Department of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0003-2368-2393
Rita ParoniClinical Biochemistry and Mass Spectrometry Laboratory, Health Sciences Department, Università degli Studi di Milano, 20142 Milan, Italy.ORCID 0000-0002-3186-8860
Laura SoldatiDepartment of Health Sciences, Università degli Studi di Milano, 20142 Milan, Italy.
University of Milan · ITIndena (Italy) · ITInstitute of Biomedical Technologies · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) subjects suffer from high risk of cardiovascular mortality, and any intervention preventing the progression of CKD may have an enormous impact on public health. In the last decade, there has been growing awareness that the gut microbiota (GM) can play a pivotal role in controlling the pathogenesis of systemic inflammatory state and CKD progression. To ameliorate the quality of life in CKD subjects, the use of dietary supplements has increased over time. Among those, curcumin has demonstrated significant in vitro anti-inflammatory properties. In this pilot study, 24 CKD patients and 20 healthy volunteers were recruited. CKD patients followed nutritional counselling and were supplemented with curcumin (Meriva

Indexed as

Dietary SupplementsAgedCase-Control StudiesCurcuminFemaleGastrointestinal MicrobiomeHumansInflammationLipid PeroxidationMalePilot ProjectsRenal Insufficiency, ChronicTreatment OutcomeUremic ToxinsCurcuminUremic Toxinschronic kidney diseasecurcumingut microbiotainflammationlipid peroxidationMerivauremic toxins

Identifiers

PMID35011106
PMCPMC8747135
OpenAlexW4206500460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.