ArticleNutrients2021
The Relationship between Gut Microbiome and Cognition in Older Australians.
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Interplay between Gut Microbiota and Cognitive Functioning in the Healthy Aging Population: A Systematic Review.Nutrients · 2024Pooled it
- Age-Related Cognitive Decline, Focus on Microbiome: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2023Pooled it
- Gut Microbiota Impact on Cognitive Function in Humans.Nutrients · 2026Review
- Maternal docosahexaenoic acid supplementation shapes offspring gut microbiota to modulate the gut-brain axis in a sow-piglet model.Frontiers in nutrition · 2026Article
- Characterization of the gut microbiome of wildFrontiers in microbiomes · 2026Article
- Item recognition is associated with gut microbiota composition in healthy humans.bioRxiv : the preprint server for biology · 2025Article
- Severe Cognitive Decline in Long-term Care Is Related to Gut Microbiome Production of Metabolites Involved in Neurotransmission, Immunomodulation, and Autophagy.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Impacts of night shift on medical professionals: a pilot study of brain connectivity and gut microbiota.Frontiers in neuroscience · 2025Article
- Maternal Gut Microbiome-Mediated Epigenetic Modifications in Cognitive Development and Impairments: A New Frontier for Therapeutic Innovation.Nutrients · 2024Review
- Investigating Causal Associations between the Gut Microbiota and Dementia: A Mendelian Randomization Study.Nutrients · 2024Article
- Article
- The Role of the Gut Microbiome in Health and Disease in the Elderly.Current gastroenterology reports · 2024Review
- Ambient long-term exposure to organophosphorus pesticides and the human gut microbiome: an observational study.Environmental health : a global access science source · 2024Observational
- The effect of Aβ seeding is dependent on the presence of knock-in genes in theFrontiers in dementia · 2022Article
- Liuwei Dihuang Decoction Alleviates Cognitive Dysfunction in Mice With D-Galactose-Induced Aging by Regulating Lipid Metabolism and Oxidative StressFrontiers in neuroscience · 2022Article
- Metabolic factors, gut microbiota, and cognitive performance: Mendelian randomization analysis.Journal of Alzheimer's disease reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ageing is associated with changes in biological processes, including reductions in cognitive functions and gut microbiome diversity. However, not much is known about the relationship between cognition and the microbiome with increasing age. Therefore, we examined the relationship between the gut microbiome and cognition in 69 healthy participants aged 60-75 years. The gut microbiome was analysed with the 16S rRNA sequencing method. The cognitive assessment included the Cognitive Drug Research computerised assessment battery, which produced five cognitive factors corresponding to 'Quality of Episodic Secondary Memory', 'Quality of Working Memory', 'Continuity of Attention, 'Speed of Memory' and 'Power of Concentration'. Multiple linear regression showed that the bacterial family
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.