Evidence map›Paper›PMID 35010896›Full record

ArticleNutrients2021

Exercise Performance Upregulatory Effect of R-α-Lipoic Acid with γ-Cyclodextrin.

Yuki Hashimoto, Katsuhiko Yoshizawa, Yuka Kaido, Akiko Takenouchi, Keiji Terao, Hiroyuki Yasui, Yutaka Yoshikawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yuki HashimotoDepartment of Health Sports Nutrition, Faculty of Health and Welfare, Kobe Women's University, Hyogo 650-0046, Japan.
Katsuhiko YoshizawaDepartment of Innovative Food Sciences, School of Food Sciences and Nutrition, Mukogawa Women's University, Hyogo 663-8183, Japan.ORCID 0000-0002-3996-032X
Yuka KaidoDepartment of Health Sports Nutrition, Faculty of Health and Welfare, Kobe Women's University, Hyogo 650-0046, Japan.
Akiko TakenouchiDepartment of Innovative Food Sciences, School of Food Sciences and Nutrition, Mukogawa Women's University, Hyogo 663-8183, Japan.
Keiji TeraoCycloChem Company Limited, Hyogo 650-0047, Japan.ORCID 0000-0001-6563-095X
Hiroyuki YasuiDepartment of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, 5 Misasagi, Nakautityo, Yamashina-ku, Kyoto 607-8414, Japan.ORCID 0000-0003-3317-3947
Yutaka YoshikawaDepartment of Health Sports Nutrition, Faculty of Health and Welfare, Kobe Women's University, Hyogo 650-0046, Japan.
Kobe Women's University · JPMukogawa Women's University · JPKyoto Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Lipoic acid (ALA) is a vitamin-like substance that is an indispensable supporting factor for a large number of enzymes. Due to its optical activity, ALA has optical isomers RALA and SALA. The major role of RALA is in energy metabolism. However, RALA cannot be used as a pharmaceutical or nutraceutical because it is sensitive to heat and acid conditions. Previous studies have shown that RALA complexed with γ-cyclodextrin (CD) has a higher antioxidant capacity than that of free RALA. The antioxidant enzyme system protects against intense exercise-induced oxidative damage and is related to the physical status of athletes. The aim of this study was to examine the effect of CD/RALA complex supplementation on antioxidant activity and performance during high-intensity exercise. Twenty-four male C3H/HeSlc mice were divided into four groups (

Indexed as

Physical Conditioning, AnimalPhysical Functional PerformanceAnimalsAntioxidantsDrug Therapy, Combinationgamma-CyclodextrinsMaleMiceMice, Inbred C3HMolecular StructureSwimmingThioctic AcidAntioxidantsgamma-cyclodextringamma-CyclodextrinsThioctic Acidoxidative stressswimming exerciseα-lipoic acidγ-cyclodextrin complex

Identifiers

PMID35010896
PMCPMC8746793
OpenAlexW4200502896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.