Evidence map›Paper›PMID 35010682›Full record

ArticleInternational journal of environmental research and public health2021

Risk Indicators Improve the Prescription Quality of Drugs with Anticholinergic Properties in Nursing Homes.

Stéphane Sanchez, Jan Chrusciel, Biné Mariam Ndiongue, Caroline Blochet, Jean François Forget, Aude Letty, Paul Emile Hay, Jean Luc Novella

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stéphane SanchezPole Territorial Santé Publique et Performance, Hôpitaux Champagne Sud, 10003 Troyes, France.ORCID 0000-0002-0925-6948
Jan ChruscielPole Territorial Santé Publique et Performance, Hôpitaux Champagne Sud, 10003 Troyes, France.
Biné Mariam NdiongueFondation Korian Pour le Bien Vieillir, 75008 Paris, France.
Caroline BlochetMedissimo, 78300 Poissy, France.
Jean François ForgetScience Department Vidal, 92130 Issy les Moulineaux, France.
Aude LettyFondation Korian Pour le Bien Vieillir, 75008 Paris, France.
Paul Emile HayFondation Korian Pour le Bien Vieillir, 75008 Paris, France.
Jean Luc NovellaEA 3797, Santé Publique, Vieillissement, Qualité de vie et Réadaptation des Sujets Fragiles, Université Reims Champagne Ardennes, 51100 Reims, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of this study was to assess the impact of a collaborative therapeutic optimization program on the rate of potentially inappropriate prescription of drugs with anticholinergic properties in nursing homes.

methodsQuasi-experimental study in 37 nursing homes in France. The intervention included the use of quality indicators for prescriptions combined with educational sessions and dedicated materials for nursing home staff (unlimited access to study material for staff, including nurses, general practitioners, pharmacists). Indicators were calculated based on routine data collected from an electronic pill dispenser system. The primary outcome was the presence of at least one prescription containing ≥1 drug from a list of 12 drugs with anticholinergic properties. A difference-in-differences analysis was conducted at 18 months as well as propensity score weighting to minimize any potential indication bias. A generalized estimating equation model estimated the probability of being prescribed at least one target drug at any time during a 9-month period for each resident.

resultsIn total, 33 nursing homes (intervention group:

conclusionThis study found that an intervention based on indicators derived from routine prescription data was effective in reducing use of drugs with anticholinergic properties prescriptions in nursing homes.

Indexed as

Cholinergic AntagonistsPharmaceutical PreparationsDrug PrescriptionsFranceHumansNursing HomesCholinergic AntagonistsPharmaceutical Preparationsanticholinergicmanagement indicatorsnursing homespotentially inappropriate prescriptions

Identifiers

PMID35010682
PMCPMC8744764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.