Evidence map›Paper›PMID 35010667›Full record

ArticleInternational journal of environmental research and public health2021

Defining Antibody Seroprevalence and Duration of Humoral Responses to SARS-CoV-2 Infection and/or Vaccination in a Greek Community.

Ourania S Kotsiou, Dimitrios Papagiannis, Evangelos C Fradelos, Dimitra I Siachpazidou, Garifallia Perlepe, Angeliki Miziou, Athanasios Kyritsis, George D Vavougios, Georgios Kalantzis, Konstantinos I Gourgoulianis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ourania S KotsiouFaculty of Nursing, School of Health Sciences, University of Thessaly, Gaiopolis, 41110 Larissa, Greece.ORCID 0000-0001-5219-6971
Dimitrios PapagiannisPublic Health & Vaccines Lab, Department of Nursing, School of Health Sciences, University of Thessaly, Gaiopolis, 41110 Larissa, Greece.ORCID 0000-0001-6123-559X
Evangelos C FradelosFaculty of Nursing, School of Health Sciences, University of Thessaly, Gaiopolis, 41110 Larissa, Greece.ORCID 0000-0003-0244-9760
Dimitra I SiachpazidouDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.ORCID 0000-0002-7688-8072
Garifallia PerlepeDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Angeliki MiziouDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Athanasios KyritsisDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.
George D VavougiosDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.ORCID 0000-0002-0413-4028
Georgios KalantzisDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.
Konstantinos I GourgoulianisDepartment of Respiratory Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, 41110 Larissa, Greece.ORCID 0000-0001-9541-1010
University of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this work, we aimed to evaluate antibody-response longevity to SARS-CoV-2 infection and/or vaccination in one of the Greek communities that was worst hit by the pandemic, Deskati, five months after a previous serosurveillance and nine months after the pandemic wave initiation (October 2020).

methodsThe SARS-CoV-2 IgG II Quant method (Architect, Abbott, IL, USA) was used for antibody testing.

resultsA total of 69 subjects, who previously tested positive or negative for COVID-19 antibodies, participated in the study. We found that 48% of participants turned positive due to vaccination. 27% of participants were both previously infected and vaccinated. However, all previously infected participants retained antibodies to the virus, irrespective of their vaccination status. The antibody titers were significantly higher in previously infected participants that had been vaccinated than those who were unvaccinated and in those that had been previously hospitalized for COVID-19 than those with mild disease.

conclusionsAntibody responses to SARS-CoV-2 infection were maintained nine months after the pandemic. Vaccination alone had generated an immune response in almost half of the population. Higher antibody titers were found in the case of vaccination in previously infected subjects and especially in those with severe disease leading to hospitalization.

Indexed as

COVID-19Antibodies, ViralGreeceHumansSARS-CoV-2Seroepidemiologic StudiesVaccinationAntibodies, Viralantibody testingGreecesemi-closed communityseroprevalence

Identifiers

PMID35010667
PMCPMC8744770
OpenAlexW4205827741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.