ArticleInternational journal of environmental research and public health2021
Comparative Study of Salivary pH, Buffer Capacity, and Flow in Patients with and without Gastroesophageal Reflux Disease.
Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05437874 (Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of Gastroesophageal Reflux Disease on Salivary Flow Rate, pH and Buffer Capacity: A Systematic Review and Meta-Analysis.Journal of oral rehabilitation · 2025Pooled it
- Potential of Saliva in Stroke Patients: A Review.International journal of molecular sciences · 2026Review
- Mucoadhesive Gel Based onPharmaceutics · 2026Article
- Assessment of Salivary Parameters-pH, Buffering Capacity and Flow-Associated with Caries Susceptibility.Diagnostics (Basel, Switzerland) · 2026Article
- Pepsin-driven corrosion of orthodontic titanium alloys in candidiasis-simulated saliva: electrochemical and statistical insights.Scientific reports · 2026Article
- Stimulated Salivary Flow Rate, Salivary pH, Viscosity, and Salivary Buffer Capacity and Their Relationship With Molar Incisor Hypomineralization in Mexican Schoolchildren.BioMed research international · 2026Article
- Association between gastroesophageal reflux and bruxism: a scoping and bibliometric review.Brazilian oral research · 2026Article
- Salivary proteins, proteases, and disease pathophysiology in oral health and precision diagnostics: a narrative review.Frontiers in dental medicine · 2026Review
- Association of the microbiome with pre-epithelial barrier impairment in individuals with laryngopharyngeal reflux.BMC microbiology · 2025Article
- Comparative Study of Patients with Periodontal and Parkinson's Disease: Clinical and Salivary Aspects.Biomedicines · 2025Article
- Four-Year Longitudinal Epidemiological Study on the Association Between a Multi-Item Saliva Testing System and Oral and Gut Microbiota.Microorganisms · 2025Article
- Salivary Characteristics and Other Risk Factors Associated with the Severity of Chemical and Mechanical Tooth Wear in At-Risk Groups: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Association between gastroesophageal reflux disease and DMFT index in the PERSIAN Guilan Cohort Study.Scientific reports · 2025Article
- Salivary analysis in adults with and without root caries in South coastal population of India - A cross-sectional analytical study.Journal of conservative dentistry and endodontics · 2025Article
- A Review on Optical Biosensors for Monitoring of Uric Acid and Blood Glucose Using Portable POCT Devices: Status, Challenges, and Future Horizons.Biosensors · 2025Review
- A Rapid and Modular Nanobody Assay for Plug-and-Play Antigen Detection.bioRxiv : the preprint server for biology · 2025Article
- The Oral Microbiome and Systemic Health: Bridging the Gap Between Dentistry and Medicine.Cureus · 2025Review
- Alterations in Salivary Parameters, Dental Caries Prevalence and Attitude Towards Oral Hygiene Maintenance Among Children and Adolescents with Metabolic Control of Type 1 Diabetes Mellitus.Indian journal of pediatrics · 2025Article
- Effect of Fluoride Varnish on Enamel Microhardness: An in vitro Study.Clinical, cosmetic and investigational dentistry · 2025Article
- Drinking water instead of apple juice or no drink results in greater odds of 4 to 7 co-occurring protective oral health factors within the hour.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oral cavity has specific and individualized characteristics, with pH, saliva flow, buffer capacity, temperature, and microorganisms content influencing oral health. Currently, the prevalence of gastroesophageal reflux disease (GERD) is constantly increasing. The objective of this study was to evaluate and compare the saliva quantity at 5 min, salivary pH, and salivary buffer capacity in patients with and without GERD, necessary for establishing the correct dental treatment plan. A Saliva-Check Buffer (GC) kit was used for the determination of salivary variables. The total number of 80 patients included in the study were divided into a study group and a control group, each containing 40 patients. Saliva quantity at 5 min was lower in patients suffering from GERD. The salivary pH of these patients turned to acid values compared to the salivary pH of controls, where the values were within the normal range. In patients with GERD, the determined salivary buffer capacity was low or very low. The use of the Saliva-Check Buffer (GC) kit is a simple, easy, non-invasive and patient-accepted method, which can also be used in the dentist's office to assess the saliva buffer capacity and pH, variables that are important for establishing a correct dental treatment plan.
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