ArticleInternational journal of environmental research and public health2021
Handgrip Strength to Predict the Risk of All-Cause and Premature Mortality in Korean Adults: A 10-Year Cohort Study.
Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of Combined Aerobic and Resistance Training on Exercise Capacity, Muscle Strength, Quality of Life, and Mortality in Patients with Coronary Heart Disease: A Systematic Review with Meta-analysis.Sports medicine - open · 2026Pooled it
- Population-specific equations of age-related maximum handgrip force: a comprehensive review.PeerJ · 2024Pooled it
- Effects of Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Older Adults with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Study.The journal of nutrition, health & aging · 2023Trial
- Neural contributions to age-related handgrip weakness revealed by multi-finger force deficit and dual-task testing.GeroScience · 2026Article
- Comparison of Kinesiophobia, Upper Limb Function, and Grip Strength in Patients with Pacemakers and Coronary Artery Disease.Anatolian journal of cardiology · 2026Article
- Combined Measure of Hand Grip Strength and Body Mass Index for Predicting Excess Body Fat in a University Population in Kentucky, USA.Diagnostics (Basel, Switzerland) · 2026Article
- Sarcopenia Risk is Associated With Decreased Swallow Safety in Patients With Dysphagia.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Strength and Perceived Effort in Repetitive Upper-Limb Tasks: An OCRA Method Analysis of 900 Workers.La Medicina del lavoro · 2025Article
- Handgrip strength as a predictor of one-year mortality in elderly patients with fragility hip fracture.Aging clinical and experimental research · 2025Article
- Can handgrip strength alone detect individuals living with frailty according to the Clinical Frailty Scale?Revista da Associacao Medica Brasileira (1992) · 2025Article
- Relationship between post traumatic stress disorder and hand dimensions and hand grip strength in children aged 8-12 exposed to earthquakes.Scientific reports · 2024Article
- Handgrip strength is associated with mortality in community-dwelling older adults: the Yilan cohort study, Taiwan.BMC public health · 2023Article
- Association of absolute and relative hand grip strength with all-cause mortality among middle-aged and old-aged people.BMC geriatrics · 2023Article
- Interactive effect of serum uric acid and handgrip strength on all-cause mortality among Japanese community-dwelling people.Metabolism open · 2023Article
- Effect of combined therapies including nutrition and physical exercise in advanced cancer patients: A pooled analysis.Frontiers in nutrition · 2023Article
- The relationship between clinical measures of cognitive function and grip strength in healthy older adults.BMC geriatrics · 2022Article
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Abstract
The prospective association of muscular weakness with the risk of all-cause and premature mortality in a general population remains unknown. The aim of this study was to investigate the prospective effects of handgrip strength and muscular weakness on risk for all-cause and premature mortality over 10 years using a large nationwide sample of Korean adults. The study participants included 9229 middle and older adults (4131 males and 5098 females), using data from the Korean Longitudinal Study of Ageing 2006-2016. Muscular strength was measured using handgrip strength. Muscle weakness was defined using the sex-specific handgrip strength index based on the Asian Working Group on Sarcopenia in Older People (AWGSOP). The primary outcome was all-cause and premature mortality assessed based on the death certificate. The hazard ratio (HR) for all-cause mortality was negatively associated with level of handgrip strength independent of potential confounding factors (HR: 2.06, 95% confidence interval [CI]: 1.62-2.63 for lowest quartile vs. highest quartile). When examined using muscle weakness defined using the AWGSOP diagnosis, the mortality was 1.56 times higher in the weak group (HR: 1.56, 95% CI: 1.36-1.78). We also found that risk of premature mortality was observed in the lowest quartile (HR: 2.34, 95% CI: 1.80-3.05) and the muscle weakness group (HR: 1.80, 95% CI: 1.52-2.13) in the fully adjusted model. Our 10-year prospective cohort study showed that handgrip strength and muscle weakness are strongly associated with an increased risk of all-cause and premature mortality in healthy middle-aged and older adults.
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