Evidence map›Paper›PMID 35009599›Full record

ArticleSensors (Basel, Switzerland)2021

Predicting Fall Counts Using Wearable Sensors: A Novel Digital Biomarker for Parkinson's Disease.

Barry R Greene, Isabella Premoli, Killian McManus, Denise McGrath, Brian Caulfield

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Barry R GreeneKinesis Health Technologies Ltd., D04 V2N9 Dublin, Ireland.ORCID 0000-0003-4445-9609
Isabella PremoliBiomarker Department, Division of Experimental Medicine, H. Lundbeck A/S, 2500 Copenhagen, Denmark.
Killian McManusKinesis Health Technologies Ltd., D04 V2N9 Dublin, Ireland.ORCID 0000-0001-7156-4493
Denise McGrathSchool of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
Brian CaulfieldInsight Centre for Data Analytics, University College Dublin, Dublin, Ireland.
University College Dublin · IEKinesis Health Technologies (Ireland) · IELundbeck (Denmark) · DK

Funding

Lundbeck (Denmark) N/A
6 · The paper itself

Abstract

People with Parkinson's disease (PD) experience significant impairments to gait and balance; as a result, the rate of falls in people with Parkinson's disease is much greater than that of the general population. Falls can have a catastrophic impact on quality of life, often resulting in serious injury and even death. The number (or rate) of falls is often used as a primary outcome in clinical trials on PD. However, falls data can be unreliable, expensive and time-consuming to collect. We sought to validate and test a novel digital biomarker for PD that uses wearable sensor data obtained during the Timed Up and Go (TUG) test to predict the number of falls that will be experienced by a person with PD. Three datasets, containing a total of 1057 (671 female) participants, including 71 previously diagnosed with PD, were included in the analysis. Two statistical approaches were considered in predicting falls counts: the first based on a previously reported falls risk assessment algorithm, and the second based on elastic net and ensemble regression models. A predictive model for falls counts in PD showed a mean R

Indexed as

Parkinson DiseaseWearable Electronic DevicesBiomarkersFemaleGaitHumansMalePostural BalanceQuality of LifeBiomarkersdigital biomarkersfallsgaitinertial sensorsParkinson’s diseaseTimed Up and Go

Identifiers

PMID35009599
PMCPMC8747473
OpenAlexW4200150358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.