Evidence map›Paper›PMID 35009068›Full record

ReviewPlants (Basel, Switzerland)2021

Comparison between the Biological Active Compounds in Plants with Adaptogenic Properties (

Velislava Todorova, Kalin Ivanov, Stanislava Ivanova

Open access · goldAbstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. 25International journal of molecular sciences · 2026
    Article
  4. PlantForm-Grown Shoots ofMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. The Effects of Peruvian maca (Molecules (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. International journal of molecular sciences · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Velislava TodorovaDepartment of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.
Kalin IvanovDepartment of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.
Stanislava IvanovaDepartment of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-1282-7868
Medical University Plovdiv · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the 1960s, research into plant adaptogens began. Plants with adaptogenic properties have rich phytochemical compositions and have been used by humanity since ancient times. However, it is not still clear whether the adaptogenic properties are because of specific compounds or because of the whole plant extracts. The aim of this review is to compare the bioactive compounds in the different parts of these plants.

methodsThe search strategy was based on studies related to the isolation of bioactive compounds from

resultsThis review includes data from 259 articles. The phytochemicals isolated from

conclusionsPlant species have always played an important role in drug discovery because their effectiveness is based on the hundreds of years of experience with folk medicine in different nations. In our view, there is great potential in the near future for some of the phytochemicals found in these plants species to become pharmaceutical agents.

Indexed as

adaptogenadaptogensecdysteroneEleutherococcus senticosusLepidium meyeniiLeuzeaMacaPanax ginsengplant adaptogensRhaponticum carthamoides

Identifiers

PMID35009068
PMCPMC8747685
OpenAlexW4200389894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.