Evidence map›Paper›PMID 35008985›Full record

ArticleInternational journal of molecular sciences2022

TRAPing Ghrelin-Activated Circuits: A Novel Tool to Identify, Target and Control Hormone-Responsive Populations in TRAP2 Mice.

Iris Stoltenborg, Fiona Peris-Sampedro, Erik Schéle, Marie V Le May, Roger A H Adan, Suzanne L Dickson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Iris StoltenborgDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Fiona Peris-SampedroDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Erik SchéleDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Marie V Le MayDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Roger A H AdanDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Suzanne L DicksonDepartment of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-3822-5294
University of Gothenburg · SEUtrecht University · NL

Funding

Hjärnfonden FO2017-0180Hjärnfonden FO2018-0262Hjärnfonden FO2019-0086Novo Nordisk Foundation NNF17OC0027206Novo Nordisk Foundation NNF19OC0056694Swedish Research Council 2018-02588Swedish Research Council 2019-01051Swedish state under the agreement between the Swedish Government andthe ocunty councils in the ALF agreement ALFGBG-723681
6 · The paper itself

Abstract

The availability of Cre-based mouse lines for visualizing and targeting populations of hormone-sensitive cells has helped identify the neural circuitry driving hormone effects. However, these mice have limitations and may not even be available. For instance, the development of the first ghrelin receptor

Indexed as

Gene Expression RegulationMice, TransgenicAnimalsEatingFemaleFood PreferencesGene OrderGene TargetingGenetic VectorsGhrelinHomologous RecombinationMaleMiceNeuronsPhenotypeReceptors, GhrelinGhrelinReceptors, GhrelinAgRParcuate nucleuschemogeneticsDREADDfood choicefood intakeFos-TRAPghrelinGHSR

Identifiers

PMID35008985
PMCPMC8745172
OpenAlexW4205988759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.