Evidence map›Paper›PMID 35008984›Full record

ArticleInternational journal of molecular sciences2022

Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model.

Chih-Hsiang Fang, Chung-Kai Sun, Yi-Wen Lin, Min-Chih Hung, Hung-Ying Lin, Ching-Hung Li, I-Ping Lin, Hung-Chen Chang, Jui-Sheng Sun, Jenny Zwei-Chieng Chang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chih-Hsiang FangTrauma and Emergency Center, China Medical University Hospital, No. 2, Xueshi Rd., North Dist., Taichung City 40447, Taiwan.ORCID 0000-0002-7797-6584
Chung-Kai SunInstitute of Traditional Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei 11221, Taiwan.
Yi-Wen LinInstitute of Biomedical Engineering, College of Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei 10617, Taiwan.
Min-Chih HungDepartment of Dentistry, National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei 10048, Taiwan.
Hung-Ying LinDepartment of Dentistry, National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei 10048, Taiwan.
Ching-Hung LiDepartment of Dentistry, National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei 10048, Taiwan.
I-Ping LinDepartment of Dentistry, National Taiwan University Hospital, Hisnchu Branch, No. 25, Lane 442, Sec. 1, Jingguo Rd., Hsinchu City 30059, Taiwan.
Hung-Chen ChangGin Chen Dental Clinic, No. 31, Long Chiang Rd., Taipei 10606, Taiwan.
Jui-Sheng SunTrauma and Emergency Center, China Medical University Hospital, No. 2, Xueshi Rd., North Dist., Taichung City 40447, Taiwan.ORCID 0000-0001-6549-2171
Jenny Zwei-Chieng ChangDepartment of Dentistry, National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei 10048, Taiwan.
National Taiwan University · TWNational Taiwan University Hospital · TWChina Medical University · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology 108-2314-B-002-120-MY3
6 · The paper itself

Abstract

In this study, we fabricated gelatin/nano-hydroxyapatite/metformin scaffold (GHMS) and compared its effectiveness in bone regeneration with extraction-only, Sinbone, and Bio-Oss Collagen

Indexed as

Bone RegenerationDurapatiteGelatinGuided Tissue RegenerationNanocompositesTissue ScaffoldsAnimalsBiocompatible MaterialsBiomarkersChemical PhenomenaImmunohistochemistryMetforminMineralsModels, AnimalOsteogenesisRatsBiocompatible MaterialsBiomarkersBio-OssDurapatiteGelatinMetforminMineralsalveolar ridge preservationbone regenerationcritical size defectmetforminnanocomposite

Identifiers

PMID35008984
PMCPMC8745742
OpenAlexW4205825742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.