Evidence map›Paper›PMID 35008977›Full record

ArticleInternational journal of molecular sciences2022

Biological Evaluation and Molecular Docking Studies of Novel 1,3,4-Oxadiazole Derivatives of 4,6-Dimethyl-2-sulfanylpyridine-3-carboxamide.

Piotr Świątek, Teresa Glomb, Agnieszka Dobosz, Tomasz Gębarowski, Kamil Wojtkowiak, Aneta Jezierska, Jarosław J Panek, Małgorzata Świątek, Małgorzata Strzelecka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Synthesis, Anticancer Activity and Molecular Docking Studies of NovelInternational journal of molecular sciences · 2022
    Article
  7. Bioactive Oxadiazoles 2.0.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Piotr ŚwiątekDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0003-4613-025X
Teresa GlombDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0003-0940-8136
Agnieszka DoboszDepartment of Medical Science Foundation, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Tomasz GębarowskiDepartment of Biostructure and Animal Physiology, Wroclaw University of Environmental and Life Sciences, Kożuchowska 1/3, 51-631 Wroclaw, Poland.ORCID 0000-0002-5689-4889
Kamil WojtkowiakFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wrocław, Poland.ORCID 0000-0001-9712-6862
Aneta JezierskaFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wrocław, Poland.ORCID 0000-0001-6601-9124
Jarosław J PanekFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wrocław, Poland.ORCID 0000-0002-2952-9739
Małgorzata ŚwiątekHospital Pharmacy, University Clinical Hospital, Borowska 213, 50-556 Wrocław, Poland.ORCID 0000-0002-8742-0790
Małgorzata StrzeleckaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
Wroclaw Medical University · PLUniversity of Wrocław · PLWrocław University of Environmental and Life Sciences · PL

Funding

Ministry of Health SUB.D070.21.094
6 · The paper itself

Abstract

To date, chronic inflammation is involved in most main human pathologies such as cancer, and autoimmune, cardiovascular or neurodegenerative disorders. Studies suggest that different prostanoids, especially prostaglandin E

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationAnti-Inflammatory Agents, Non-SteroidalCell LineChemistry Techniques, SyntheticCyclooxygenase InhibitorsDensity Functional TheoryDose-Response Relationship, DrugEnzyme ActivationHumansImidazolesMolecular StructureOxadiazolesReactive Oxygen SpeciesSpectrum AnalysisStructure-Activity Relationship1,3,4-oxadiazoleAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase InhibitorsImidazolesOxadiazolesReactive Oxygen Species1,3,4-oxadiazolecyclooxygenasecytotoxicitydimethylpyridinemolecular docking

Identifiers

PMID35008977
PMCPMC8745710
OpenAlexW4205753793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.